SARA Suppresses Myofibroblast Precursor Transdifferentiation in Fibrogenesis in a Mouse Model of Scleroderma
Corano-Scheri K, Liang X, Dalal V, Le Poole IC, Varga J, Hayashida T. JCI Insight. 2022 Sep 22:e160977. doi:10.1172/jci.insight.160977. Epub ahead of print. PMID: 36136606.
Deficiency of Inhibitory TLR4 Homolog RP105 Exacerbates Fibrosis
Wang W, Bale S, Yalavarthi B, Verma P, Tsou PS, Calderone KM, Bhattacharyya D, Fisher GJ, Varga J, Bhattacharyya S. JCI Insight. 2022 Sep 22:e160684. doi: 10.1172/jci.insight.160684. Epub ahead of print. PMID: 36136452.
Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis
Sapao P, Roberson EDO, Shi B, Assassi S, Skaug B, Lee F, Naba A, White BEP, Córdova-Fletes C, Tsou PS, Sawalha AH, Gudjonsson JE, Ma F, Verma P, Bhattacharyya D, Carns M, Strauss JF 3rd, Sicard D, Tschumperlin DJ, Champer MI, Campagnola PJ, Teves ME, Varga J. J Invest Dermatol. 2022 Sep 15:S0022-202X(22)01928-5. doi: 10.1016/j.jid.2022.08.052. Epub ahead of print. PMID: 36116512.
Thy-1 Plays a Pathogenic Role and Is a Potential Biomarker for Skin Fibrosis in Scleroderma
Marangoni RG, Datta P, Paine A, Duemmel S, Nuzzo MA, Sherwood L, Varga J, Ritchlin C, Korman BD. JCI Insight. 2022 Sep 6:e149426. doi: 10.1172/jci.insight.149426. Epub ahead of print. PMID: 36066980.
Role of Cellular Senescence in the Pathogenesis of Systemic Sclerosis
Tsou PS, Shi B, Varga J. Curr Opin Rheumatol 2022 Aug 17. doi:10.1097/BOR.0000000000000898. Epub ahead of print. PMID: 35979691.
Differences in Symptom Experience Among Patients with Systemic Sclerosis: A Cluster Analytic Approach to Identifying Subgroups
Murphy SL, Chen YT, Lee YC, Carns M, Aren K, Korman B, Hinchcliff M, Varga J. Rheumatology (Oxford). 2022 Aug 3:keac444. doi: 10.1093/rheumatology/keac444. Epub ahead of print. PMID: 35920770.
Gut Microbe-Derived Metabolite Trimethylamine N-oxide Activates PERK to Drive Fibrogenic Mesenchymal Differentiation
Kim SJ, Bale S, Verma P, Wan Q, Ma F, Gudjonsson JE, Hazen SL, Harms PW, Tsou PS, Khanna D, Tsoi LC, Gupta N, Ho KJ, Varga J. iScience. 2022 Jun 26;25(7):104669. doi:10.1016/j.isci.2022.104669. PMID: 35856022; PMCID: PMC9287188.
Effect of Nintedanib on Progression of Systemic Sclerosis-Associated Interstitial Lung Disease Over 100 Weeks: Data from a Randomized Controlled Trial
Assassi S, Distler O, Allanore Y, Ogura T, Varga J, Vettori S, Crestani B, Voss F, Alves M, Stowasser S, Maher TM; SENSCIS trial investigators. ACR Open Rheumatol. 2022 Jul 19. doi: 10.1002/acr2.11483. Epub ahead of print. PMID: 35852465.
Clinical and Autoantibody Associations in Antinuclear Antibody-Positive Systemic Sclerosis Lacking Prototypic Autoantibodies
Kruzer K, Goncalves Marangoni R, Heckler I, Elhage A, Varga J, Hinchcliff M, Carns M, Aren K, Wielgosz A, Nuzzo M, Venkataraman I, Korman B. J Clin Rheumatol. 2022 Jun 29. doi: 10.1097/RHU.0000000000001881. Epub ahead of print. PMID: 35767831.
RNA-Seq Analysis Identifies Alterations of the Primary Cilia Gene SPAG17 and SOX9 Locus Non-coding RNAs in Systemic Sclerosis
Roberson EDO, Carns M, Cao L, Aren K, Goldberg IA, Morales-Heil DJ, Korman BD, Atkinson JP, Varga J Arthritis Rheumatol. 2022 Jun 28. doi: 10.1002/art.42281. Epub ahead of print. PMID: 35762854.
