Research

U-M Division of Pulmonary & Critical Care Medicine Researchers

Research performed within the Division of Pulmonary & Critical Care Medicine has greatly impacted our understanding of basic lung biology, disease pathogenesis, and targeted therapeutics. NIH grant funding for research within the Division exceeds 13 million dollars annually. Our investigative portfolio is comprehensive, with specific areas of emphasis including pulmonary inflammation, lung injury and repair, fibrotic lung disorders, host defense, lung transplantation, and lung cancer. 

New major areas of modern biology have emerged, including genetics/genomics, metagenomics, proteomics, metabolomics, stem cell biology, computational biology, and the microbiome. Researchers in the division participate in large multidisciplinary and multicenter disease-specific programs and networks in interstitial lung disease (IPFnet, COMET, LTRC), COPD (SPIROMICS, COPD gene, LTRC), and Acute Lung Injury (SCOR, SCCOR, ARDSnet). 

Emerging fields of patient-oriented research have been added or expanded, including health services research and sleep. Active areas of health services research include long-term functional outcomes in survivors of critical illness, nosocomial infection, delirium in the ICU, health care utilization, and health care policy.

Research Highlights

COVID: Sajid Javid Orders Review of Medical Device Racial Bias

Michael Sjoding, MD discusses the study he led that found a significant discrepancy in pulse oximeters' accuracy when used on patients with a darker skin tone.

UM Researchers, in Collaboration with Xoran Technologies, Receive Grant Award for Mobile Lung CT Device

Michigan Center for Integrative Research in Critical Care researchers, including Robert Dickson, MD; Michael Sjoding, MD; and MeiLan Han, MD, MS, received a NIH grant award to support the development of a mobile lung computed tomography device.

Biased Tech Could Determine Who Gets Life Saving Therapy

Research uncovers racial bias in oxygen readings during the pandemic, even among patients needing ECMO.

Stem Cells and Their Role in Lung Transplant Rejection

Vibha Lama, MBBS, MS and her lab identify cells that appear to play a pivotal role in creating the scarring, or fibrosis, characteristic of chronic rejection following a lung transplant.