Areas of Interest
My research aims to unlock the role of metabolic and epigenetic landscapes in development, physiology and cancer pathogenesis.
Credentials
- PhD, Stem Cell and Developmental Biology, University of Tsukuba, Japan
Published Articles or Reviews
- Khoa, L.T.P., Yang, W., Shan, M., Zhang, L., Mao, F., Zhou, B., Li, Q., Malcore, R., Harris, C., Zhao, L., Rao, R., Iwase, S., Kalantry, S., Bielas, S., Lyssiotis, C.A., Dou, Y. (2024). Quiescence Enables Unrestricted Cell Fate in Naive Embryonic Stem Cells. Nat Commun 15, 1721. PMID: 38409226
- Khoa, L.T.P., Tsan, Y.C., Mao, F., Kremer, D., Sajjakulnukit, P., Zhang, L., Zhou, B., Tong, X., Bhanu, N.V., Choudhary, C., Garcia, B.A., Yin, L., Smith, G.D., Saunders, T.L., Bielas, S., Lyssiotis, C.A., Dou, Y. (2020). Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation. Cell Stem Cell 27, 441-458. PMID: 32610040
- Khoa, L.T.P.#, Dou, Y#. (2020). In Vitro Derivation of Quiescent Mouse Embryonic Stem Cells Based on Distinct Mitochondrial Activity. STAR Protocols 1, 100136. PMID: 33377030. #Co-correspondence.
- Zhang, H., Khoa, L.T.P., Mao, F., Xu, H., Zhou, B., Han, Y., O'Leary, M., Nusrat, A., Saunders, T.L., Wang, L., and Dou, Y. (2019). MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency State. Cell Reports 29, 2659–2671. PMID: 31775036
- Sun, Y., Zhou, B., Mao, F., Xu, J., Miao, H., Zou, Z., Khoa, L.T.P., Cai, S., Witkin, M., Koche, R., Ge, K., Dressler, G., Levine, R.L., Armstrong, S.A., Dou, Y., Hess, J.L. (2018). HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis. Cancer Cell 34, 643–658. PMID: 30270123
- Khoa, L.T.P., and Dou, Y. (2017). Phosphoproteomics Links Glycogen Synthase Kinase-3 to RNA Splicing. J Bio Chem. 292, 18256–18257. PMID: 29101250