Functional Assessment Core

Functional Assessment module faculty and staff
Managers Naheed Khan and Cheng-mao Lin, staff member Sarah Sheskey, and director David Antonetti

Submit a work order to the Functional Assessment Core

The Functional Assessment Core provides training and support to help investigators perform non-lethal measures of ocular structure and function. Currently, the Core provides expertise in OCT, OptoMotry, ERG, fundus imaging, and pupillometry. Please call or email us to discuss your project needs and how the Functional Assessment Core can help advance your research.

Equipment

The equipment can be reserved for use after training. Reserve Equipment here. A computer workstation is also available for data processing.

Bioptigen Envisu Preclinical Spectral Domain Optical Coherence Imaging System

  • Real-time non-invasive imaging of the microstructure of retinal tissue in small laboratory animals (rats and mice)
  • Acquire, process, display and save depth-resolved images of ocular microstructure
  • Repeat imaging for longitudinal studies
Bioptigen Envisu Preclinical Spectral Domain Optical Coherence Imaging System

Cerebral Mechanics OptoMotry System

  • Real time behavioral testing of optokinetic response for small laboratory animals (rats and mice)
  • Visual acuity and contrast sensitivity testing
  • Repeat testing for longitudinal studies
Cerebral Mechanics OptoMotry System

Phoenix Micron III Retinal Imaging System

  • Bright field and fluorescent retinal imaging for small laboratory animals (rats and mice)
  • High resolution images in live animals
  • Repeat imaging for longitudinal studies
Phoenix Micron III Retinal Imaging System

NeurOptics A-2000 Small Animal Pupillometer System

  • Tracking and recording pupil size change in small laboratory animals (rats and mice) in real time
  • Binocular camera system with two independently controlled visible light sources in 4 colors and infrared illumination for various stimulation modes
  • Repeat imaging for longitudinal studies
NeurOptics A-2000 Small Animal Pupillometer System

Diagnosys Celeris Electrophysiology System

  • Perform full-field dark-adapted and light-adapted ERGs
  • Ability to stimulate both eyes independently
  • Ability to run tests with one eye as a reference, or test both eyes simultaneously
  • Capability to perform pattern ERGs
  • Repeat testing for longitudinal studies

Diagnosys Celeris Electrophysiology System

Diagnosys Espion E2 Electrophysiology System

  • The Espion E2 electrophysiology system comprises hardware, software and stimulators to perform full-field dark-adapted and light-adapted electroretinograms (ERGs) and other electrophysiological tests.
  • Custom protocols include single flash rod response, single flash cone response, flicker response, scotopic threshold response, ON-OFF response, oscillatory potentials, photopic negative response.
  • Stimulator
    • LEDs, produce any color flash and background. 
    • Xenon flash for brighter flashes, maximum intensity is 3000 cd.s/m2.  
  • The recording set up consists of a grounded and shielded Faraday cage and temperature controlled warming bed.
  • Capability to perform pattern ERGs
Diagnosys Espion E2 Electrophysiology System