Action is needed to keep innovation going on brain-based disease and behavior, while helping young neuroscientists prepare for careers
ANN ARBOR, Mich. — Call them the Brain Generation — the tens of thousands of college and graduate students working toward degrees in neuroscience, and the high school students who want to join them someday.
They’ve grown up in a time when exciting new discoveries about the brain come out every day, fueled by a revolution in scientific tools during their short lives. And that has fueled a boom in students choosing to work toward a neuroscience degree.
But even as they study and train, they’re worried about their futures — and whether they’ll get to use their brains to the fullest in a time of tight research funding.
Top senior neuroscientists are worried too. That’s why a team of them has just published a report filled with recommendations about how neuroscience education must change. Only by doing so, they say, will we keep the discoveries coming while preparing these bright young people for many paths — not just the traditional university research career.
Writing in the journal Neuron, they present key insights and recommendations that grew out of a fall 2014 workshop held by the Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine.
“This should be the best of times for both the scientists and the field,” they write. “The shared task of all the stakeholders — academia, government, industry, scientific societies, foundations, and other components of the private and public sectors — is to ensure that we do not kill this hope.”
Huda Akil, Ph.D., a University of Michigan Medical School neuroscientist who’s the paper’s corresponding author, looks back on the incredible growth in the field over the past two decades and sees reason for hope, not pessimism, for the new generation. But, she says, it’s up to university programs to adapt to the new reality that more than half their graduates will someday work outside academia, and train them appropriately.
“The number of opportunities is huge, within and outside academic institutions,” she says. “This is a perfect moment for neuroscience in particular, when the field is blossoming and growing with many ideas, tools, approaches, and intersections with other fields, and huge interest among young people. It’s a perfect recipe for success – the question is how to proceed so we don’t squash that opportunity.”
Akil and her co-authors, who come from industry, government, universities and a private foundation, lay out some key calls to action, including:
- incorporating more computational science, statistics and programming into neuroscience training, to help students handle with the massive amounts of data generated by modern tools including brain imaging, genetic sequencing, molecular analysis, bioinformatics and more
- promoting skills that can help students communicate with and work in teams with researchers from other fields, from genetics, math, physics and engineering to the social sciences and philosophy, or even other sub-fields of neuroscience
- informing students about the range of careers available to them, and the challenges and opportunities involved in each, through courses and internships -- while still keeping the path to academic research careers strong
- developing two types of training programs – one to prepare traditional “neuroscientists” who will focus on making basic discoveries about the brain and its disorders, and one for those who will go into a more “applied” field in industry, nonprofit, policy and other areas – to ensure they get a solid background in neuroscience
- improving the representation of women and diverse groups in neuroscience careers, and better support for the personal life trajectories of all students, especially in academia where women are underrepresented on the faculty despite making up the majority of graduate students
- finding new ways for universities to fund graduate training in the biosciences, beyond the usual federal grants, and assisting young scientists in finding private funds to offset the declining supply of federal research dollars
- creating career path of “staff scientists” in American universities, who can work on the teams of traditional neuroscience professors without having to climb the traditional academic ladder
“We are likely losing promising scientists from the academic career path,” the authors write, because of the stagnation in federal research funding, and the perception by younger neuroscientists that the path to academic success and secure funding has become nearly impossible to climb.
They point with hope to efforts made by U.S. federal research funding agencies to provide innovative funding for training. But they say universities and other sectors must also change, at a time when many nations have launched massive neuroscience efforts such as the U.S. Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, China Brain, the Japan Brain/MINDS Project, and the Human Brain Project in Europe.
“We need to be giving out hopeful signals that it’s not a horrible risk to get a Ph.D. in neuroscience, and that you can make discoveries about the brain and apply them in many ways,” says Akil, a past president of the Society for Neuroscience and co-director of U-M’s Molecular and Behavioral Neuroscience Institute. She holds the Gardner Quarton Distinguished University Professorship in Neurosciences and is a member of the Medical School’s Department of Psychiatry faculty.
Akil especially points to the growing role for neuroscience-trained professionals in the technology sector – not just the traditional biotechnology and pharmaceutical path, but high-tech computing-based companies that want to use new knowledge about behavior in apps and gadgets.
“The more people in society want to understand their own behavior, control their behavior such as eating and exercise, improve their memories and attention, and more, the more we can apply what we’re learning in neuroscience about brain function and how it changes with various conditions or natural aging,” she says. “We have a lot to figure out going forward, and we needs all hands on deck. Anyone smart enough, passionate enough and willing to be flexible and bring ideas together, we need them to stay with us.”
In addition to Akil, the paper’s authors are Rita Balice-Gordon of Pfizer, David Lopes Cardozo of Harvard Medical School, Walter Koroshetz of the National Institute of Neurological Disorders and Stroke, Sheena Maria Posey Norris, of the National Academies, Todd Sherer of the Michael J. Fox Foundation for Parkinson’s Research, S. Murray Sherman of the University of Chicago and Edda Thiels of the National Science Foundation.
REFERENCE: Neuron, Akil et al: “Neuroscience Training for the 21st Century” http://www.cell.com/neuron/fulltext/S0896-6273 (16)30209-4 / 10.1016/j.neuron.2016.05.030
Join the conversation in a RedditAMA on June 10th, 1-3 p.m. EST. The link will be posted on the front page of Reddit at 7 am EST. Participants include: Huda Akil, Floh Thiels, Todd Sherer, David Cardozo, Walter Koroshetz, and Murray Sherman. To register, visit: http://info.cell.com/neuron-reddit-science-ama-2016.
The authors’ views are personal views and do not necessarily represent those of the NIH and NSF, the Federal Government, or the National Academies of Sciences, Engineering, and Medicine.