ARVO 2019 Annual Meeting

In a rapidly changing world, eye and vision researchers are emerging from the lab and the clinic to engage the public, patients and policymakers regarding the sight-saving work that we do and the benefits it brings to our societies. Our passion for our work and commitment to evidence-based science and medicine empower these conversations as they occur around the world. 

April 27, 2019

  • 10:35 AM - 11:00 AM
    Course: Interactions between microglia and Müller cells in diabetic retinopathy
    West 212-214
    Steven Abcouwer

April 28, 2019

  • 8:00 AM - 9:45 AM
    Poster: Animal Imaging
    A0605: Real-time guidance and monitoring of CNV through subretinal injection in rabbit eyes using multimodal PAM and OCT imaging system
    West Exhibition Hall                                     
    Yannis Paulus
  • 8:00 AM - 9:45 AM   
    Poster: AMD anti-VEGF II       
    A0290: Survey of Intravitreal Injection Practice Patterns among Retina Specialists
    West Exhibition Hall
    Therese Sassalos, Nish Patel, Chris Andrews, David C. Musch, Cagri G. Besirli
  • 8:00 AM - 9:45 AM    
    Poster: Physiology/Pharmacology
    A0099: Electrophysiological Responses of Isolated Retinal Pigment Epithelial (RPE) Cells to Physiological Concentrations of Thiocyanate
    West Exhibition Hall
    Bret Hughes
  • 8:00 AM - 10:00 AM  
    Symposium:The potential and pitfalls of big data
    Big Data Sets: Leveraging existing data sources for Big Data analyses in ophthalmology
    East Ballroom C
    Joshua Stein, MD
  • 1:00 PM - 2:30 PM    
    SIG
    New ideas about metabolic interactions between photoreceptors and Müller cells
    East 8&15
    Cagri G. Besirli
  • 1:00 PM - 2:45 PM    
    Poster: Clinical and epidemiological aspects of infection
    B0319: Medication burden for patients with bacterial keratitis  
    West Exhibition Hall
    Maria A. Woodward, Megan Tuohy
  • 1:00 PM - 2:45 PM    
    Poster: Corneal neovascularization
    B0486: Removal of suture-induced corneal neovascularization in rabbits using concurrently applied nanosecond laser pulses and ultrasound
    West Exhibition Hall
    Yixin Yu, Maria A. Woodward, Yannis Paulus
  • 1:00 PM - 2:45 PM    
    Poster: Cataract Surgery         
    A0487: Predictors of Non-adherence to Follow-up after Cataract Surgery: Results from the PCIOL Study                                      
    West Exhibition Hall              
    Emily Eton
  • 1:00 PM - 2:45 PM    
    Poster: Clinical Melanoma. Therapy and Complications            
    B0197: Two year results of a phase 1b/2 open-label clinical trial of AU-011 for the treatment of small to medium choroidal melanoma   
    West Exhibition Hall                                      
    Hakan Demirci
  • 1:50 PM - 2:05 PM    
    Workshop                                   
    Industry-Academic Collaborations for Mutual Benefit       
    West 220  
    Steven Abcouwer
  • 3:00 PM - 4:45 PM    
    Poster: Visual Impairment - Impact on Daily Activities                
    A0006: Gait Patterns in Severe Peripheral Field Loss due to Retinitis Pigmentosa                             
    West Exhibition Hall              
    Joshua Ehrlich, Abigail Kumagai, Andrew Chen, Phuoc Nguyen, Sherry Day, Donna Wicker, Ashley Howson, David C. Musch, James D. Weiland, Sayoko Moroi
  • 3:00 PM - 4:45 PM    
    Poster:  Diabetic eye disease 
    A0061: Association of Socioeconomic Variables with Risk Factors for Diabetic Retinopathy  
    West Exhibition Hall                    
    Anjali Shah
  • 4:30 PM - 4:45 PM    
    Paper: Healthcare Delivery      
    Understanding barriers to glaucoma treatment adherence among patients in South India   
    West 220                                       
    Olivia Killeen, Paula Anne Newman-Casey
  • 7:30 PM - 9:30 PM    
    Alumni Reception                                                                             
    Rogue Kitchen and Wetbar – Convention Centre location      
    Paul Lee: Host

April 29, 2019

  • 8:15 AM - 10:00 AM
    Poster: Machine Learning I
    A0128: Deep neural network and human evaluation of referral-warranted diabetic retinopathy using smartphone-based retinal photographs
    West Exhibition Hall
    Leslie Niziol, David C. Musch, Yannis Paulus
  • 8:15 AM - 10:00 AM
    Poster: Deep Learning & AI
    A0214: Development of AI Deep Learning Algorithms for the Quantification of Retinopathy of Prematurity
    West Exhibition Hall
    Emily Zepeda
  • 8:15 AM - 10:00 AM
    Poster: Machine Learning II
    A0164: Deep learning-based automatic segmentation of stromal infiltrates and associated biomarkers on slit-lamp images of microbial keratitis
    West Exhibition Hall
    Megan Tuohy, Maria A. Woodward
  • 8:15 AM - 10:00 AM
    Poster: Metabolic and Oxidative Control of Retinal Homeostasis and Diseases
    B0316: Photoreceptor Metabolic Reprogramming in an In-Vivo Model of NaIO3 Induced Retinal Degeneration
    West Exhibition Hall
    Omar Moinuddi, Eric Weh, Cagri G. Besirli
  • 8:15 AM - 10:00 AM
    Poster: Retinal Vascular Biology
    B0276: The tight junction protein occludin regulates endothelial cell proliferation
    West Exhibition Hall
    Xuwen Liu, David A. Antonetti
  • 8:30 AM - 8:45 AM
    Paper: Advances in Retinoblastoma and Radiation Retinopathy The Histone Methyltransferase NSD2 is a New Histopathologic Biomarker and Potential Therapeutic Target for Human Retinoblastoma.
    East 1
    Rajesh Rao, Zhenhua Zou
  • 11:15 AM - 1:00 PM
    Poster: Glaucoma risk factors, progression, and management
    A0517: The Association between Glaucoma Medication Adherence and Intraocular Pressure Variability in the Collaborative Initial Glaucoma Treatment Study (CIGTS)
    West Exhibition Hall
    David C. Musch, Leslie Niziol, Paula Anne Newman-Casey
    View the poster
  • 11:15 AM - 1:00 PM
    Poster: Glaucoma risk factors, progression, and management
    A0538: Modeling the societal costs of poor glaucoma medication adherence
    West Exhibition Hall
    Paula Anne Newman-Casey
    View the poster
  • 11:15 AM - 1:00 PM
    Poster: Corneal imaging and topography
    B0406: Reliability of physicians’ measurements when manually annotating images of microbial keratitis
    West Exhibition Hall
    Matthias Kriegel, Megan Tuohy, Leslie Niziol, Maria A. Woodward
    View the poster
  • 11:15 AM - 1:00 PM
    Poster: Corneal imaging and topography
    B0431: Deep learning segmentation of the mouse cornea from anterior segment OCT in the presence of non-corneal and non-physiologic structures
    West Exhibition Hall
    Nambi Nallasamy
  • 11:15 AM - 1:00 PM
    Poster: Cataract Surgery II
    B0374: Refining Metrics for Assessing the Quality of Care of Patients Undergoing Cataract Surgery for Use in Big Data Analyses
    West Exhibition Hall
    Eric Weinlander, Nidhi Talwar, Jennifer Weizer, Alan Sugar, Paul Lee, Joshua Stein
  • 12:00 PM - 12:15 PM
    Paper: Retinal Bioenergetics and Metabolic Interactions Primary fetal RPE cultures resist accumulation and toxicity of lipofuscin-like material, and accumulated material can be further reduced by autophagy induction
    East 11/12
    Qitao Zhang, Feriel Presswalla, Sally Temple, Jeffrey Stern, David N. Zacks, Debra A. Thompson, Jason Miller
  • 12:15 PM - 12:30 PM
    Paper: Diabetic Retinopathy Therapeutics Anti-VEGF Therapy for Diabetic Retinopathy: Consequences of Inadvertent Treatment Interruptions
    East Ballroom B
    Mark Johnson, Thomas Wubben
  • 12:45 PM - 1:00 PM
    Paper: Retinal Bioenergetics and Metabolic Interactions The neuroprotective role of Hexokinase 2 in photoreceptor survival
    East 11/12
    Eric Weh, Mercy Pawar, Cagri G. Besirli
  • 1:15 PM - 2:45 PM
    SIG
    Glia in blood-retina barrier disorders
    East 1
    Steven Abcouwer
  • 4:00 PM - 5:45 PM
    Poster: Diabetic Retinopathy: Pathogenic Mechanisms
    B0223: Endothelial expression of permeability-resistant occludin mutant preserves visual function in diabetes
    West Exhibition Hall
    Cheng-mao Lin, Andreia Goncalves, Sarah Sheskey, David A. Antonetti
  • 4:00 PM - 5:45 PM
    Poster: Diabetic Retinopathy: Pathogenic Mechanisms
    B0234: Dual protective action of αA-crystallin on retinal glial and neuronal cells during metabolic stress
    West Exhibition Hall
    Madhu Nath, Yang Shan, Patrice E. Fort
  • 4:00 PM - 5:45 PM
    Poster: Biochemistry and Molecular Biology of the Retina
    A0382: Elevated levels of A2E and lipofuscin fluorescence in the retinal pigment epithelium of mice that lack retinol dehydrogenase RDH8 are decreased by dark rearing
    West Exhibition Hall
    Debra Thompson
  • 4:00 PM - 5:45 PM
    Poster: Visual Fields, Psychophysics, and Electrophysiology
    A0636: Identifying Patients at Risk for Experiencing Rapid Progression of Open Angle Glaucoma Using Supervised Machine Learning
    West Exhibition Hall
    Chris Andrews, Joshua D. Stein
  • 4:00 PM - 5:45 PM
    Poster: IOP Measurement
    A0580: Postural Change in Intraocular Pressure and Agreement between Goldmann Applanation, Tonopen, and Perkins Tonometry
    West Exhibitition Hall
    Sayoko Moroi
  • 4:00 PM - 5:45 PM
    Poster: Biochemistry/Molecular Biology
    B0209: Effects of diabetes on retinal protein lysine malonylation
    West Exhibitition Hall
    Steven Abcouwer, Sumathi Shanmugam, Heather Hager, Cheng-mao Lin, Thomas Gardner, Patrice Fort
  • 4:00 PM - 5:45 PM
    Poster: Clinical Studies
    A0559: Early clinical experience with latanoprostene bunod
    West Exhibitition Hall
    David Reed, Jesse Gilbert, Sayoko Moroi
  • 4:00 PM - 5:45 PM
    Poster:Corneal Dry Eye Clinical II Epidemiology
    B0485: The prevalence of ocular Graft Versus Host Disease on a Facebook forum
    West Exhibitition Hall
    Sherry Day, Karen DeLoss
  • 5:30 PM - 5:45 PM
    Paper: Neuroprotection Fas signaling triggers glial-mediated neuroinflammation in glaucoma
    East Ballroom C
    David Zacks

April 30, 2019

  • 8:45 AM - 10:30 AM
    Poster: AMD
    A0244: X-Chromosome Inactivation is a Biomarker of Clinical Severity in Female Carriers of X-linked Retinitis Pigmentosa
    West Exhibition Hall
    Abigail Fahim, Kari Branham, Mohammad Othman, Athanasios Karoukis, Chris Andrews, John Heckenlively
  • 8:45 AM - 10:30 AM
    Paper: Visual Fields, Psychophysics, and Electrophysiology Using a Machine Learning Technique Called Kalman Filtering to Forecast Conversion from Ocular Hypertension to Primary Open Angle Glaucoma East
    Ballroom A
    Chris Andrews, Joshua D. Stein
  • 8:45 AM - 10:30 AM
    Poster: Animal Models for Visual Disease and Restoration
    A0506: Midkine-a deficiency causes cell cycle arrest and reactive gliosis in zebrafish Müller glia following photoreceptor cell death
    West Exhibition Hall
    Mikiko Nagashima, Peter F. Hitchcock
  • 11:45 AM - 1:30 PM
    Poster: Consequences of vision impairment
    B0069: Association between Vision Loss and Screening Mammography among Women with Medicare
    West Exhibition Hall
    Annie Wu, Nidhi Talwar, Sean Hansen, Paul Lee, Joshua Stein
    View the poster
  • 11:45 AM - 1:30 PM
    Paper: Retina/RPE New drugs, Mechanisms of action, and Toxicility Expanded clinical spectrum of pentosan polysulfate sodium-associated pigmentary maculopathy
    East 2/3
    Stephen Armenti, Thiran Jayasundera,  Joshua Stein
  • 11:45 AM - 1:30 PM
    Poster: Consequences of vision impairment
    B0067: The impact of comorbid visual impairment and dementia on activity limitations in older adults
    West Exhibition Hall
    Nish Patel, Joshua Ehrlich
  • 2:45 PM - 4:30 PM
    Poster: Retinal Microglia and Neuroinflammation
    A0519: Knockout of the Toll-like Receptors (TLR) 2 and 4 Affects the Recruitment of Microglia/Macrophages to the Stressed Photoreceptor Cells in Response to Retinal Detachment
    West Exhibition Hall
    Joanne Choi, Bing Ross, Jingyu Yao, Lin Jia, Steven Abcouwer, David Zacks
  • 2:45 PM - 4:30 PM
    Poster: Visual Impairment - Assistive Devices and Rehabilitation
    B0092: Design of Smart Head-Mounted Display Technology: A Qualitative Study West
    Exhibition Hall V
    Swetha Jeganathan, Abigail Kumagai,  Sayoko Moroi, James Weiland, Joshua Ehrlich
    View the Poster
  • 2:45 PM - 4:30 PM
    Poster: Retinal Degenerations - Cilia and Ciliopathies
    A0486: Ciliary Delivery of the CNG-gated Channel in Rod Photoreceptors
    West Exhibition Hall
    Jillian Pearring, Jason Reed Willer

May 1, 2019

  • 8:15 AM - 10:00 AM
    Poster: Anatomical changes during ocular morphogenesis and disease
    A0019: Qualitative assessment of human posterior poles procured with the RE-One chamber versus the traditional method.
    West Exhibition Hall
    Yang Shan, Patrice E. Fort
  • 8:15 AM - 10:00 AM
    Poster: Prevalence of vision impairment
    A0343: Prevalence and Correlates of Vision Impairment and Age-Related Eye Diseases Among Post-Menopausal Women: Study of Women's Health Across the Nation, Michigan Site.
    West Exhibition Hall
    Navasuja Kumar, Sarah Wood, David C. Musch, Sayoko Moroi
  • 8:45 AM - 9:00 AM
    Paper: Retinal Degeneration Protective effect of shifting protein degradation from autophagy to proteasome on retinal degeneration in P23H mice
    East 8&15
    Jingyu Yao, Yaoyan Qiu, Lin Jia, Kecia Feathers, Debra Thompson, David Zacks
  • 9:15 AM - 9:30 AM
    Paper: Epidemiology of Corneal Disease Demographic and temporal variation in incidence of herpes zoster ophthalmicus in the United States population
    West 220
    Nakul Shekhawat, Nidhi Talwar, Joshua Stein
  • 10:15 AM - 12:00 PM
    Poster: Retinal disease: molecular mechanisms and gene editing
    A0269: Retinal degenerative diseases alter vitreous protein and extracellular vesicle concentrations
    West Exhibition Hall
    Thomas Gardner
  • 10:15 AM - 12:00 PM
    Poster: Visual Impairment and Patient Reported Outcomes
    A0379: Functioning and Vision-Related Quality of Life in Severe Peripheral Field Loss due to Retinitis Pigmentosa: A Outcome Measure Development Project
    West Exhibition Hall
    Ryan Lange, Abigail Kumagai, Katherine Bissen, Paul Lee, Joshua Ehrlich
  • 10:15 AM - 12:00 PM
    Poster: Macular Diseases Excluding AMD
    A0493: Characterizing two novel mouse models of Ctrp5/C1qtnf5 to understand disease mechanism in late-onset retinal degeneration
    West Exhibition Hall
    Naheed Khan
  • 10:30 AM - 10:45 AM
    Paper: Corneal biomechanics, keratoconus and crosslinking Impact of scleral contact lens use on risk of requiring corneal transplantation for keratoconus
    West 211
    Jennifer Ling, Shahzad Mian, Joshua Stein, Moshiur Rahman, Maria Woodward
  • 3:00 PM - 4:45 PM
    Poster: Cornea and diabetes-related disorders
    B0311: Variants in myelin regulatory factor (MYRF) cause autosomal dominant nanophthalmos
    West Exhibition Hall
    Lev Prasov, Sayoko Moroi, Steven Archer, Laurel Wiinikka-Buesser, Frank Rozsa, Julia Richards
  • 3:00 PM - 4:45 PM
    Poster: Ocular Blood Flow
    B0515: Effects of Timolol and Latanoprost on Ocular Perfusion Pressure in Eyes of Healthy Volunteers
    West Exhibition Hall
    Ajay Kolli, David Reed, David C. Musch, Sayoko Moroi
  • 3:00 PM - 4:45 PM
    Poster: Healthcare Delivery
    B0337: Differences in Receiving Eye Care Based on Dementia Status
    West Exhibition Hall
    Moshiur Rahman, Chris Andrews, Joshua Stein
  • 3:00 PM - 4:45 PM
    Poster: Healthcare Delivery B0360: Reporting and enrollment of women and racial minorities in ophthalmic clinical trials
    West Exhibition Hall
    Lindsey De Lott, Jennifer Ling, Maria Woodward
  • 3:00 PM - 4:45 PM
    Poster: Healthcare Delivery
    B0361: Compliance with Two-Identifier Protocols for Patient Verification
    West Exhibition Hall
    Erik Sweet, Constance Spak, Jennifer Weizer
  • 4:00 PM - 4:15 PM
    Paper: Neuroprotection Potential cancer therapy for activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, provides photoreceptor neuroprotection
    East 11/12
    Thomas Wubben, Mercy D. Pawar, Eric Weh, Andrew Smith, Cagri G. Besirli
  • 6:15 PM - 7:45 PM
    SIG
    New Perspectives on MIGS
    East 8&15
    Sayoko Moroi

May 2, 2019

  • 8:00 AM - 9:45 AM
    Poster: Photoreceptor Cell & Developmental Biology
    A0549: PRCD supports the organized structure of the photoreceptor outer segment
    West Exhibition Hall
    Jillian Pearring
  • 8:00 AM - 9:45 AM
    Poster: Retinal Development
    A0529: Roles of Mechanistic Target of Rapamycin Complexes in Retinal Development and Visual Function
    West Exhibition Hall
    Dejuan Kong, Heather Hager, Sumathi Shanmugam, Lynda Elghazi, Patrice Fort, Thomas Gardner, Steven Abcouwer
  • 10:15 AM - 10:30 AM
    Paper: Pharmacological Interventions and Cellular Interventions Long-term stable intraocular pressure (IOP) control and optic nerve head (ONH) preservation following AAV-mediated ocular gene therapy in a canine model of ADAMTS10-open-angle glaucoma (OAG) ARVO
    Ballroom
    Sayoko Moroi
  • 10:15 AM - 12:00 PM
    Poster: Cornea Dry Eye Clinical Treatment
    B0253: DREAM Extension Study - Comparison of placebo and omega-3 fatty acid supplement groups on OSDI, 4 key signs of DED and adverse events
    West Exhibition Hall
    Munira Hussain, Roni Shtein
    View the poster
  • 10:15 AM - 12:00 PM
    Poster: Cornea Dry Eye Clinical Treatment
    B0271: Determinants of Ocular Discomfort Severity Among Participants in the Dry Eye Assessment and Management (DREAM) Study
    West Exhibition Hall
    Roni Shtein
  • 10:15 AM - 12:00 PM
    Poster: Cataract, Cornea, and Ocular Surface Disease
    A0094: Demographic and temporal variation in incidence of herpes simplex virus keratitis in the United States
    West Exhibition Hall
    Nidhi Talwar, Joshua D. Stein, Nakul Shekhawat
  • 10:15 AM - 12:00 PM
    Poster: Cataract, Cornea, and Ocular Surface Disease
    A0068: Opioid Prescribing and Use after Corneal Surgeries
    West Exhibition Hall
    Yibing Zhang, Nicholas Behunin, Leslie Niziol, Bradford Tannen, Maria A. Woodward
    View the poster
  • 10:15 AM - 12:00 PM
    Poster: Uveitis / ocular inflammatory disease: Epidemiology, clinical characteristics and QoL
    B0131: Correlation of immunohistochemical markers with disease and clinical outcome measures in patients with autoimmune retinopathy
    West Exhibition Hall
    Thiran Jayasundera, John Heckenlively, Steven Lundy
  • 10:15 AM - 12:00 PM
    Poster: Retinal Detachment, Trauma and Repair
    A0305: Protective role of mesencephalic astrocyte-derived neurotrophic factor (MANF) in photoreceptor death
    West Exhibition Hall
    Mercy D. Pawar, Cagri G. Besirli
  • 10:15 AM - 12:00 PM
    Poster: Diabetic Retinopathy and Surgery
    A0184: Natural History of Visual Function Impairment in Patients Post-treatment with Pan-retinal Photocoagulation for Proliferative Diabetic Retinopathy
    West Exhibition Hall
    Xing Chen, Amro Omari, Min Hwang, Thomas Gardner
    View the Poster
  • 11:30 AM - 11:45 AM
    Paper: Biochemistry and molecular biology of diabetic retinopathy Retinal Ganglion Cell Protein Synthesis is Regulated by Glycolysis, mTORC1 Signaling, and Diabetes
    East Ballroom C
    Mandy Losiewicz, Lynda Elghazi, Dejuan Kong, Patrice Fort, Steven Abcouwer, Thomas Gardner