ARVO 2018 Annual Meeting

In a rapidly changing world, eye and vision researchers are emerging from the lab and the clinic to engage the public, patients and policymakers regarding the sight-saving work that we do and the benefits it brings to our societies. Our passion for our work and commitment to evidence-based science and medicine empower these conversations as they occur around the world. 

April 28, 2018

  • 8:15 AM 8:35 AM
    Course: Big Data: Principles to practical application 
    Presentation: Tapping into Health Care Claims Databases to Learn About Ocular Diseases
    Room 313A
    Joshua Stein, MD, MS
  • 1:00 PM 1:25 PM
    Course: Big Data: Principles to practical application
    Presentation: Practical Considerations for Performing Analyses Using Health Care Claims Data 
    Room 313A
    Joshua Stein, MD, MS
  • 8:15 AM 10:00 AM
    Poster: Retinitis pigmentosa (clinical) 
    Presentation: A0063: Investigating plasticity in Retinitis Pigmentosa using retinotopic representation of the lesion projection zone
    Exhibit Hall
    James Weiland

April 29, 2018

  • 9:30 AM 9:50 AM
    Symposia: Proteostasis networks: challenges and therapeutic opportunities for ocular diseases 
    Presentation: Photoreceptor autophagy: role in maintaining homeostasis
    Room 310
    David Zacks, MD, PhD
  • 9:53 AM 10:11 AM
    Lecture: Retinal architecture and function: new insights 
    Presentation: Retinal glia - physiology and disease
    Ballroom A
    Thomas Gardner, MD, MS
  • 1:00 PM 2:45 PM
    Poster: New Insights on Retinogenesis from Organoids
    B0186: COMPASS acts as a temporal rheostat to control retinal neuroectoderm versus mesoderm fate choice
    Exhibit Hall
    Rajesh Rao, MD
  • 1:00 PM 2:45 PM
    Poster: Vision Rehabilitation Devices and Training
    Presentation: C0070: Head Mounted Display Technology for Low Vision due to Peripheral Field Loss
    Exhibit Hall
    David Musch, MD, MPH, Donna Wicker, OD, Sherry Day, OD, Ashley Howson, MS, OTR/L, James Weiland, PhD, Sayoko Moroi, MD, PhD, Joshua Ehrlich, MD, MPH

April 30, 2018

  • 8:15 AM 10:00 AM
    Poster: Corneal Surgery nonrefractive
    B0007: Safety of Long-term Storage and Shipping of p3DMEK
    Exhibit Hall
    Jason Hooton, MD, Shahzad Mian, MD
  • 8:15 AM 10:00 AM
    Poster: Genetics of AMD andMacular dystrophies
    B0352: The journey from clinical to genetic diagnosis in Stargardt disease
    Exhibit Hall
    Dana Schlegel, MS, MPH, CGC, Kari Branham, MS, CGC, John Heckenlively, MD, Abigail Fahim, MD, PhD, Thiran Jayasundera, MD
  • 8:15 AM 10:00 AM
    Poster: AMD and Anti-VEGF II
    C0032: Assessment of the outflow drainage system in AMD after multiple anti-VEGF intravitreous injections
    Exhibit Hall Maria Fernanda Abalem
  • 8:15 AM 10 AM
    Poster Session: Clinical Trials and Drug Studies
    Exhibit Hall
    David Musch, PhD, MPH, Moderator
  • 8:15 AM 8:30 AM
    Paper: Biochemistry and Molecular Biology of Diabetic Retinopathy
    Presentation: Regional Changes of the Retinal Transcriptome in Humans: Diabetes or Retinopathy signature?
    Room 320
    Patrice Fort, PhD, MS, Yang Shan
  • 8:15 AM 8:30 AM
    Paper: EOM and associated tissues: Disease and Development
    Presentation: Three-dimensional ex vivo modeling of Graves' orbitopathy reveals a novel pathogenic role for the HIF2ALOX pathway
    Room 306AB
    Alon Kahana, MD, PhD, Terry Smith, MD
  • 8:45 AM 9:00 AM
    Paper: EOM and associated tissues: Disease and Development
    Presentation: Retinoid-regulated expression of pro-inflammatory cytokines in orbital tissues: a potential common denominator in orbital inflammatory syndromes
    Room 306AB
    Philip Kish, PhD, Alon Kahana, MD, PhD
  • 9:30 AM 9:45 AM
    Paper: EOM and associated tissues: Disease and Development
    Presentation: Adult Abducens Nerve and Lateral Rectus Muscle Regenerate in a Coordinated Fashion Following Injury, Revealing Important Biological Interactions
    Room 306AB
    Alon Kahana, MD, PhD, Philip Kish, PhD
  • 11:15 AM 1:00 PM
    Poster: Retinoblastoma: From Bench to Bedside
    A0005: PI3K and MEK Signaling and Effects of Kinase Inhibitors in a Retinoblastoma Cell Model
    Exhibit Hall
    Andrew Smith, Mercy Pawar, Cagri Besirli, MD, PhD
  • 11:15 AM 1:00 PM Poster: Retinoblastoma: From Bench to Bedside 
    A0007: Selective death of Y79 retinoblastoma cells by magnetic hyperthermia via caspase dependent apoptotic pathway
    Exhibit Hall
    Mercy Pawar, Cagri Besirli, MD, PhD, Hakan Demirci, MD
  • 11:15 AM 1:00 PM Poster: Image Processing and Interpretation
    A0192: Automated Algorithmic Analysis of OCT Scans for Vitreous Hyperreflective Foci in Patients with Retinal Vein Occlusion
    Exhibit Hall
    Edward Korot, David Antonetti, PhD
  • 11:15 AM 1:00 PM
    Poster: Diabetic Retinopathy: Clinical 
    C0290: Analysis of Retinal  Function in Patients with Proliferative Diabetic Retinopathy Treated with Panretinal Photocoagulation
    Exhibit Hall
    Naheed Khan, PhD, Amro Omari, Thomas Gardner, MD, MS
  • 11:15 AM 1:00 PM
    Poster: Diabetic Retinopathy: Clinical 
    C0291: Predictors of Anti-VEGF Treatment Initiation and Frequency in Diabetic Patients 
    Exhibit Hall
    Thomas Gardner, MD, MS, Anjali Shah, MD
  • 11:15 AM 1:00 PM
    Poster: Diabetic Retinopathy: Clinical 
    C0304: Baseline characteristics of diabetic patients presenting to a retina clinic
    Exhibit Hall  
    Thomas Gardner, MD, MS, Anjali Shah, MD
  • 11:15 AM 1:00 PM
    Minisymposium: Circadian clocks in retinal health and diseases
    Room 315
    David Zacks, MD, Phd, Moderator
  • 11:15 AM 11:30 AM
    Paper: AMD and Anti-VEGF
    Presentation: Clinical feasibility of ultra-rapid, non-pharmacologic anesthesia for intravitreal injection in patients receiving anti-VEGF treatment
    Ballrooms BC
    Cagri Besirli, MD, PhD, David Zacks, MD, PhD, Thomas Gardner, MD, MS, Anjali Shah, MD
  • 11:15 AM 1:00 PM
    Poster Session: Diabetic Retinopathy: Imaging
    C0314 -C0341
    Thomas Gardner, MD, MS, Moderator
  • 3:30 PM 5:15 PM
    Poster: Biomechanics
    A0050: Relationship between corneal hysteresis and positional change in intraocular pressure in healthy adults
    Exhibit Hall
    Sayoko Moroi, MD, PhD, David Reed, David Musch, PhD, MPH
  • 3:30 PM 5:15 PM
    Poster: Eye Movements
    A0341: Epigenetic regulation of myocyte dedifferentiation and myofiber growth during zebrafish EOM regeneration  
    Exhibit Hall
    Phillip Kish, PhD, Alon Kahana, MD, PhD
  • 3:30 PM 5:15 PM
    Poster: Early and Atrophic AMD 
    C0117: Preclinical safety study of ultra-rapid, nonpharmacologic anesthesia for intravitreal injections
    Exhibit Hall
    Cagri Besirli, MD, PhD
  • 3:30 PM 5:15 PM
    Poster Session: Early and Atrophic AMD 
    C0098 - C0125 
    Jason Miller, MD, PhD, Moderator
  • 3:30 PM 3:45 PM
    Paper: Highlights of Imaging Technologies 
    Presentation: Retinotopic Imaging of the Central Visual Pathway in Optic Nerve and Outer Retinal Disease
    Room 313A
    James Weiland, PhD
  • 4:30 PM 4:45 PM
    Paper: IOP Measurement, Clinical Trials and Drug Studies 
    Presentation: Stepped Medication Use, Associated Symptoms, and Treatment Failure among Participants in the Medication Arm of the Collaborative Initial Glaucoma Treatment Study
    Room 316C
    David Musch, PhD, MPH, Leslie Niziol, Paul Lichter, MD, MS
  • 4:52 PM 5:07 PM
    Minisymposium: From optics to electronics: New technologies for improving vision in health and disease - 
    Presentation: Electronic retinal prosthesis: concepts and clinical results
    Room 316A
    James Weiland, PhD

May 1, 2018

  • 8:15 AM 10:00 AM
    Poster: Glaucoma risk factors, progression and management
    B0116: Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: Interphysician Agreement for Screening Images
    Exhibit Hall
    Paul Lee, MD, JD
  • 8:45 AM 9:00 AM
    Paper: Retinal Development
    Presentation: Conditional knockout of mTORC1 in retina blocks developmental formation of the astrocyte network and retinal vasculature
    Room 315
    Steven Abcouwer, PhD, Dejuan Kong, Lynda Elghazi-Cras, Patrice Fort, PhD, MD, Thomas Gardner, MD, MS
  • 11:15 AM 1:00 PM
    Poster: Macular diseases excluding AMD
    A0243: A Novel Contrast Sensitivity Test as a New Measure of Visual Function in Central Serous Chorioretinopathy
    Exhibit Hall
    Merina Thomas, MD, David Zacks, MD, PhD
  • 11:15 AM 1:00 PM
    Poster: Dry eye non-clinical I
    C0075: Role of ion channels in the response of conjunctival goblet cells to dry eye
    Exhibit Hall Donald Puro, MD, PhD
  • 11:15 AM 11:30 AM
    Paper: Diabetic retinopathy: Molecular mechanisms and novel therapeutic targets
    Presentation: Very long chain ceramides production mediated by ELOVL4 stabilizes tight junctions and prevents diabetes-induced retinal vascular permeability
    Room 315
    Xuwen Liu, MD, PhD, David Antonetti, PhD
  • 12:45 PM 1:00 PM
    Paper: Diabetic retinopathy: Molecular mechanisms and novel therapeutic targets
    Presentation: Contribution of occludin S490 phosphorylation on blood retinal barrier integrity and visual function
    Room 315
    Andreia Goncalves, PhD, Sarah Sheskey, Chengmao Lin, PhD, David Antonetti, PhD
  • 1:30 PM 3:00 PM
    Workshop: Bridging and bootstrapping in today's risk averse environment
    Room 314
    Cagri Besirli, MD, PhD, Steven Abcouwer, PhD, Moderators
  • 1:59 PM 2:11 PM Workshop: Bridging and bootstrapping in today's risk averse environment
    Presentation: Financing a start-up when you work at a university
    Room 314
    David Zacks, MD, PhD
  • 3:30 PM 5:15 PM
    Poster: Diabetic retinopathy - preclinical studies  
    A0199: Trapping all trans-retinal is protective to vascular damage in ischemia reperfusion
    Exhibit Hall
    David Antonetti, PhD, Chengmao Lin, PhD, Steven Abcouwer, PhD
  • 3:30 PM 5:15 PM
    Poster: Cataract, cornea, and ocular surface disease
    C0030: Assessment of intraocular pressure at the end of cataract surgery: comparison between etimated and measured value
    Exhibit Hall
    Maria Fernanda Abalem,  MBChB, PhD
  • 3:30 PM 5:15 PM
    Poster: Melanoma: clinical innovations
    A0298: How to measure the largest basal diameter of the choroidal melanoma: a mathematical study
    Exhibit Hall
    Bernadete Ayres, MD Hakan Demirci, MD

May 2, 2018

  • 6:45 AM 8:15 AM
    Breakfast with an Expert
    Translational Research
    313BC, Table 1
    Thomas Gardner, MD, MS
  • 8:15 AM 10:00 AM
    Poster: RPE: metabolism
    A0157: Measuring and Modulating Lipid Handling Pathways in the RPE: Implications for Age-Related Macular Degeneration
    Exhibit Hall
    Jason Miller, MD, PhD, Feriel Presswalla, Qitao Zhang, David Zacks, MD, PhD, Debra Thompson, PhD
  • 8:15 AM 10:00 AM
    Poster: Prevalence of vision impairment
    B0222: Association of Vision Impairment and Depressive Symptoms Among Midlife Women: Study of Woman's Health Across the Nation
    Exhibit Hall
    Navasuja Kumar, David Musch, PhD, MPH, Sayoko Moroi, MD, PhD
  • 8:15 AM 10:00 AM
    Poster: Retinal Detachment: Basic and Clinical Science
    C0064: Role of autophagy activation on photoreceptor survival in retinal detachment
    Exhibit Hall
    Jingyu Yao, MD, PhD, Lin Jia, MS, David Zacks
  • 8:15 AM 10:00 AM
    Poster: Retinal Detachment: Basic and Clinical Science
    C0085: A primate model of sustained retinal detachment
    Exhibit Hall
    David Zacks, MD, PhD
  • 8:15 AM 10:00 AM
    Poster: Retinal vascular diseases I (excluding diabetes)
    C0158: Aflibercept versus bevacizumab and/or ranibizumab for recurrent macular edema secondary to central retinal vein occlusion
    Exhibit Hall
    Cagri Besirli, MD, PhD
  • 11:15 AM 1:00 PM
    Poster: Inflammatory/immune responses in retinal diseases
    A0203: ER-stress and mesencephalic astrocyte-derived neurotrophic factor (MANF) in an in vitro model of photoreceptors
    Exhibit Hall
    Mercy Pawar, Cagri Besirli, MD, PhD
  • 11:15 AM 1:00 PM
    Poster: Inflammatory/immune responses in retinal diseases
    A0206: Disheveled localizes at tight junction sites and interacts with ZO1 in BREC
    Exhibit Hall
    Monica Diaz-Coranguez, PhD, Cheng-mao Lin, PhD, David Antonetti, PhD
  • 11:15 AM 1:00 PM
    Poster: Imaging Technologies and Applications I
    A0263: Smartphone-based wide-field fundus photography for accurate diagnosis of pediatric retinal diseases
    Exhibit Hall
    Tapan Patel, MD, PhD, Tyson Kim, MD, PhD, Philip Lieu, MD, Cagri Besirli, MD, PhD, Hakan Demirci, MD, Yannis Paulus, MD
  • 11:15 AM 1:00 PM
    Poster: Diabetic Macular Edema Clinical Research
    C0212: The Role of Midperipheral Retinal Nonperfusion in Diabetic Macular Edema
    Exhibit Hall
    Amro Omari, Rajesh Rao, MD, Anjali Shah, MD, Thiran Jayaundera, MD, Thomas Gardner, MD, MS
  • 11:15 AM 1:00 PM
    Poster: Diabetic Macular Edema Clinical Research 
    C0193: Short-term effects of  intravitreal Bevacizumab in contrast sensitivity of patients with diabetic macular edema and optimizing glycemic control
    Exhibit Hall
    Maria Fernanda Abalem,  MBChB, PhD
  • 11:15 AM 11:30 AM
    Paper: Novel genes found through methods old and new 
    Presentation: Mutations in the novel gene IFT88 are involved in causing non-syndromic inherited retinal degeneration (IRD)
    Room 316C
    Kari Branham, MD, CGC, John Heckenlively, MD
  • 11:45 AM 12:00 PM
    Paper: Novel genes found through methods old and new 
    Presentation: Deciphering the genetic architecture of IRD by integrated analysis of 425 whole genomes 
    Room 316C 
    Kari Branham, MD, CGC, John Heckenlively, MD
  • 11:45 AM 12:00 PM
    Paper: Impact of vision impairment 
    Presentation: High Prevalence of Falls, Fear of Falling and Impaired Balance in Older Adults with Vision Impairment
    Room 316B
    Joshua Ehrlich, MD, MPH, Brian Stagg, MD
  • 11:45 AM 12:00 PM
    Paper: Gene function and neural protection
    Presentation: Photoreceptor metabolic reprogramming provides survival advantage in acute stress while causing chronic degeneration 
    Room 315 Thomas Wubben, MD, PhD, Mercy Pawar, Andrew Smith, Heather Hager, MS, Cagri Besirli, MD, PhD
  • 12:45 PM 1:00 PM
    Paper: Novel genes found through methods old and new 
    Presentation: Genetic Testing Adds Research and Clinical Value to a Retinal Degeneration Registry
    Room 316C
    Kari Branham, MS, CGC
  • 3:30 PM 5:15 PM
    Poster: Healthcare delivery
    B0335: Geographic Variation in Medicare Part D Spending on Ophthalmic Drugs 
    Exhibit Hall
    Nathan Liles, MD, MPH, Maria Woodward, MD, MS, Paula Anne Newman-Casey, MD, MS, Lindsay Delott, MD
  • 3:30 PM 5:15 PM
    Poster: Healthcare delivery
    B0340: Perceived autonomy support from the healthcare team is associated with glaucoma medication adherence
    Exhibit Hall
    Paula Anne Newman-Casey, MD, MS, Leslie Niziol, Paul Lee, MD, JD
  • 3:30 PM 3:45 PM
    Paper: Signaling in retinal degeneration 
    Presentation: Retinal Detachment Triggers an Innate Immune Response in the Retina 
    Room 315
    Bing Ross, MD, PhD, Jingyu Yao, Sumathi Shanmugam, Steven Abcouwer, PhD, David Zacks, MD, PhD
  • 8:00 PM 10:00 PM
    ARVO Classical Concert at the Hilton Hawaiian Village
    Mozart: Parto! From Clemenze di Tito
    Hilton Hawaiian Village 2005 Kalia Rd. 
    Dana Schlegel

May 3, 2018

  • 8:15 AM 10:00 AM
  • Poster: Lymphoma, hemangioma, surface, orbit, and eyelid tumors
    Exhibit Hall
    Moderator: Hakan Demirci, MD
  • 8:15 AM 10:00 AM
    Poster: Retinal vascular diseases II (excluding diabetes)
    A0113: Cilioretinal Artery Occlusion Associated with Optic Disc Edema
    Exhibit Hall
    Eric Weinlander, MD, Thomas Wubben, MD, PhD, Merina Thomas, MD, Katherine Davis, MD, Wayne Cornblath, MD, Mark Johnson, MD
  • 8:15 AM 10:00 AM
    Poster: Retinal vascular diseases II (excluding diabetes)
    A0121: Familial Retinal Arteriolar Tortuosity and Quantification of Vascular Tortuosity Using Swept-Source Optical Coherence Tomography Angiography
    Exhibit Hall
    Thao Phuong Le, MD
  • 8:15 AM 10:00 AM
    Poster: Animal Imaging
    C0139: Image-guided photomediated ultrasound therapy as a novel method to selectively treat eye vasculature
    Exhibit Hall
    Yannis Paulus, MD
  • 8:15 AM 10:00 AM
    Poster: Animal Imaging
    C0120: Multimodal photoacoustic microscopy, OCT, and fluorescence imaging system to detect retinal neovascularization in rabbit eyes
    Exhibit Hall
    Yanxiu Li, Yannis Paulus, MD
  • 8:15 AM 10:00 AM
    Poster: Imaging: Anterior Segment
    C0173: Interplicata distance as part of ciliary body biometry to understand complications of plateau iris configuration
    Exhibit Hall
    David Reed, Bernadete Ayres, MD, Sayoko Moroi, MD, PhD
  • 11:00 AM 12:45 PM
    Poster: Neuroprotection
    C0258: A small peptide inhibitor of the Fas receptor prevents axon degeneration and death of retinal ganglion cells in a microbead-induced mouse model of glaucoma.
    Exhibit Hall
    David Zacks, MD, PhD
  • 11:35 AM 11:50 AM
    Minisymposium: Retinal lipid and glucose metabolism in health and disease
    Presentation: Protein synthesis and lipid metabolism as key pathogenic processes of retinal sensibility to diabetes
    Room 315
    Patrice Fort, PhD, MS