April 28, 2018
- 8:15 AM 8:35 AM
Course: Big Data: Principles to practical application
Presentation: Tapping into Health Care Claims Databases to Learn About Ocular Diseases
Room 313A
Joshua Stein, MD, MS - 1:00 PM 1:25 PM
Course: Big Data: Principles to practical application
Presentation: Practical Considerations for Performing Analyses Using Health Care Claims Data
Room 313A
Joshua Stein, MD, MS - 8:15 AM 10:00 AM
Poster: Retinitis pigmentosa (clinical)
Presentation: A0063: Investigating plasticity in Retinitis Pigmentosa using retinotopic representation of the lesion projection zone
Exhibit Hall
James Weiland
April 29, 2018
- 9:30 AM 9:50 AM
Symposia: Proteostasis networks: challenges and therapeutic opportunities for ocular diseases
Presentation: Photoreceptor autophagy: role in maintaining homeostasis
Room 310
David Zacks, MD, PhD - 9:53 AM 10:11 AM
Lecture: Retinal architecture and function: new insights
Presentation: Retinal glia - physiology and disease
Ballroom A
Thomas Gardner, MD, MS - 1:00 PM 2:45 PM
Poster: New Insights on Retinogenesis from Organoids
B0186: COMPASS acts as a temporal rheostat to control retinal neuroectoderm versus mesoderm fate choice
Exhibit Hall
Rajesh Rao, MD - 1:00 PM 2:45 PM
Poster: Vision Rehabilitation Devices and Training
Presentation: C0070: Head Mounted Display Technology for Low Vision due to Peripheral Field Loss
Exhibit Hall
David Musch, MD, MPH, Donna Wicker, OD, Sherry Day, OD, Ashley Howson, MS, OTR/L, James Weiland, PhD, Sayoko Moroi, MD, PhD, Joshua Ehrlich, MD, MPH
April 30, 2018
- 8:15 AM 10:00 AM
Poster: Corneal Surgery nonrefractive
B0007: Safety of Long-term Storage and Shipping of p3DMEK
Exhibit Hall
Jason Hooton, MD, Shahzad Mian, MD - 8:15 AM 10:00 AM
Poster: Genetics of AMD andMacular dystrophies
B0352: The journey from clinical to genetic diagnosis in Stargardt disease
Exhibit Hall
Dana Schlegel, MS, MPH, CGC, Kari Branham, MS, CGC, John Heckenlively, MD, Abigail Fahim, MD, PhD, Thiran Jayasundera, MD - 8:15 AM 10:00 AM
Poster: AMD and Anti-VEGF II
C0032: Assessment of the outflow drainage system in AMD after multiple anti-VEGF intravitreous injections
Exhibit Hall Maria Fernanda Abalem - 8:15 AM 10 AM
Poster Session: Clinical Trials and Drug Studies
Exhibit Hall
David Musch, PhD, MPH, Moderator - 8:15 AM 8:30 AM
Paper: Biochemistry and Molecular Biology of Diabetic Retinopathy
Presentation: Regional Changes of the Retinal Transcriptome in Humans: Diabetes or Retinopathy signature?
Room 320
Patrice Fort, PhD, MS, Yang Shan - 8:15 AM 8:30 AM
Paper: EOM and associated tissues: Disease and Development
Presentation: Three-dimensional ex vivo modeling of Graves' orbitopathy reveals a novel pathogenic role for the HIF2ALOX pathway
Room 306AB
Alon Kahana, MD, PhD, Terry Smith, MD - 8:45 AM 9:00 AM
Paper: EOM and associated tissues: Disease and Development
Presentation: Retinoid-regulated expression of pro-inflammatory cytokines in orbital tissues: a potential common denominator in orbital inflammatory syndromes
Room 306AB
Philip Kish, PhD, Alon Kahana, MD, PhD - 9:30 AM 9:45 AM
Paper: EOM and associated tissues: Disease and Development
Presentation: Adult Abducens Nerve and Lateral Rectus Muscle Regenerate in a Coordinated Fashion Following Injury, Revealing Important Biological Interactions
Room 306AB
Alon Kahana, MD, PhD, Philip Kish, PhD - 11:15 AM 1:00 PM
Poster: Retinoblastoma: From Bench to Bedside
A0005: PI3K and MEK Signaling and Effects of Kinase Inhibitors in a Retinoblastoma Cell Model
Exhibit Hall
Andrew Smith, Mercy Pawar, Cagri Besirli, MD, PhD - 11:15 AM 1:00 PM Poster: Retinoblastoma: From Bench to Bedside
A0007: Selective death of Y79 retinoblastoma cells by magnetic hyperthermia via caspase dependent apoptotic pathway
Exhibit Hall
Mercy Pawar, Cagri Besirli, MD, PhD, Hakan Demirci, MD - 11:15 AM 1:00 PM Poster: Image Processing and Interpretation
A0192: Automated Algorithmic Analysis of OCT Scans for Vitreous Hyperreflective Foci in Patients with Retinal Vein Occlusion
Exhibit Hall
Edward Korot, David Antonetti, PhD - 11:15 AM 1:00 PM
Poster: Diabetic Retinopathy: Clinical
C0290: Analysis of Retinal Function in Patients with Proliferative Diabetic Retinopathy Treated with Panretinal Photocoagulation
Exhibit Hall
Naheed Khan, PhD, Amro Omari, Thomas Gardner, MD, MS - 11:15 AM 1:00 PM
Poster: Diabetic Retinopathy: Clinical
C0291: Predictors of Anti-VEGF Treatment Initiation and Frequency in Diabetic Patients
Exhibit Hall
Thomas Gardner, MD, MS, Anjali Shah, MD - 11:15 AM 1:00 PM
Poster: Diabetic Retinopathy: Clinical
C0304: Baseline characteristics of diabetic patients presenting to a retina clinic
Exhibit Hall
Thomas Gardner, MD, MS, Anjali Shah, MD - 11:15 AM 1:00 PM
Minisymposium: Circadian clocks in retinal health and diseases
Room 315
David Zacks, MD, Phd, Moderator - 11:15 AM 11:30 AM
Paper: AMD and Anti-VEGF
Presentation: Clinical feasibility of ultra-rapid, non-pharmacologic anesthesia for intravitreal injection in patients receiving anti-VEGF treatment
Ballrooms BC
Cagri Besirli, MD, PhD, David Zacks, MD, PhD, Thomas Gardner, MD, MS, Anjali Shah, MD - 11:15 AM 1:00 PM
Poster Session: Diabetic Retinopathy: Imaging
C0314 -C0341
Thomas Gardner, MD, MS, Moderator - 3:30 PM 5:15 PM
Poster: Biomechanics
A0050: Relationship between corneal hysteresis and positional change in intraocular pressure in healthy adults
Exhibit Hall
Sayoko Moroi, MD, PhD, David Reed, David Musch, PhD, MPH - 3:30 PM 5:15 PM
Poster: Eye Movements
A0341: Epigenetic regulation of myocyte dedifferentiation and myofiber growth during zebrafish EOM regeneration
Exhibit Hall
Phillip Kish, PhD, Alon Kahana, MD, PhD - 3:30 PM 5:15 PM
Poster: Early and Atrophic AMD
C0117: Preclinical safety study of ultra-rapid, nonpharmacologic anesthesia for intravitreal injections
Exhibit Hall
Cagri Besirli, MD, PhD - 3:30 PM 5:15 PM
Poster Session: Early and Atrophic AMD
C0098 - C0125
Jason Miller, MD, PhD, Moderator - 3:30 PM 3:45 PM
Paper: Highlights of Imaging Technologies
Presentation: Retinotopic Imaging of the Central Visual Pathway in Optic Nerve and Outer Retinal Disease
Room 313A
James Weiland, PhD - 4:30 PM 4:45 PM
Paper: IOP Measurement, Clinical Trials and Drug Studies
Presentation: Stepped Medication Use, Associated Symptoms, and Treatment Failure among Participants in the Medication Arm of the Collaborative Initial Glaucoma Treatment Study
Room 316C
David Musch, PhD, MPH, Leslie Niziol, Paul Lichter, MD, MS - 4:52 PM 5:07 PM
Minisymposium: From optics to electronics: New technologies for improving vision in health and disease -
Presentation: Electronic retinal prosthesis: concepts and clinical results
Room 316A
James Weiland, PhD
May 1, 2018
- 8:15 AM 10:00 AM
Poster: Glaucoma risk factors, progression and management
B0116: Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: Interphysician Agreement for Screening Images
Exhibit Hall
Paul Lee, MD, JD - 8:45 AM 9:00 AM
Paper: Retinal Development
Presentation: Conditional knockout of mTORC1 in retina blocks developmental formation of the astrocyte network and retinal vasculature
Room 315
Steven Abcouwer, PhD, Dejuan Kong, Lynda Elghazi-Cras, Patrice Fort, PhD, MD, Thomas Gardner, MD, MS - 11:15 AM 1:00 PM
Poster: Macular diseases excluding AMD
A0243: A Novel Contrast Sensitivity Test as a New Measure of Visual Function in Central Serous Chorioretinopathy
Exhibit Hall
Merina Thomas, MD, David Zacks, MD, PhD - 11:15 AM 1:00 PM
Poster: Dry eye non-clinical I
C0075: Role of ion channels in the response of conjunctival goblet cells to dry eye
Exhibit Hall Donald Puro, MD, PhD - 11:15 AM 11:30 AM
Paper: Diabetic retinopathy: Molecular mechanisms and novel therapeutic targets
Presentation: Very long chain ceramides production mediated by ELOVL4 stabilizes tight junctions and prevents diabetes-induced retinal vascular permeability
Room 315
Xuwen Liu, MD, PhD, David Antonetti, PhD - 12:45 PM 1:00 PM
Paper: Diabetic retinopathy: Molecular mechanisms and novel therapeutic targets
Presentation: Contribution of occludin S490 phosphorylation on blood retinal barrier integrity and visual function
Room 315
Andreia Goncalves, PhD, Sarah Sheskey, Chengmao Lin, PhD, David Antonetti, PhD - 1:30 PM 3:00 PM
Workshop: Bridging and bootstrapping in today's risk averse environment
Room 314
Cagri Besirli, MD, PhD, Steven Abcouwer, PhD, Moderators - 1:59 PM 2:11 PM Workshop: Bridging and bootstrapping in today's risk averse environment
Presentation: Financing a start-up when you work at a university
Room 314
David Zacks, MD, PhD - 3:30 PM 5:15 PM
Poster: Diabetic retinopathy - preclinical studies
A0199: Trapping all trans-retinal is protective to vascular damage in ischemia reperfusion
Exhibit Hall
David Antonetti, PhD, Chengmao Lin, PhD, Steven Abcouwer, PhD - 3:30 PM 5:15 PM
Poster: Cataract, cornea, and ocular surface disease
C0030: Assessment of intraocular pressure at the end of cataract surgery: comparison between etimated and measured value
Exhibit Hall
Maria Fernanda Abalem, MBChB, PhD - 3:30 PM 5:15 PM
Poster: Melanoma: clinical innovations
A0298: How to measure the largest basal diameter of the choroidal melanoma: a mathematical study
Exhibit Hall
Bernadete Ayres, MD Hakan Demirci, MD
May 2, 2018
- 6:45 AM 8:15 AM
Breakfast with an Expert
Translational Research
313BC, Table 1
Thomas Gardner, MD, MS - 8:15 AM 10:00 AM
Poster: RPE: metabolism
A0157: Measuring and Modulating Lipid Handling Pathways in the RPE: Implications for Age-Related Macular Degeneration
Exhibit Hall
Jason Miller, MD, PhD, Feriel Presswalla, Qitao Zhang, David Zacks, MD, PhD, Debra Thompson, PhD - 8:15 AM 10:00 AM
Poster: Prevalence of vision impairment
B0222: Association of Vision Impairment and Depressive Symptoms Among Midlife Women: Study of Woman's Health Across the Nation
Exhibit Hall
Navasuja Kumar, David Musch, PhD, MPH, Sayoko Moroi, MD, PhD - 8:15 AM 10:00 AM
Poster: Retinal Detachment: Basic and Clinical Science
C0064: Role of autophagy activation on photoreceptor survival in retinal detachment
Exhibit Hall
Jingyu Yao, MD, PhD, Lin Jia, MS, David Zacks - 8:15 AM 10:00 AM
Poster: Retinal Detachment: Basic and Clinical Science
C0085: A primate model of sustained retinal detachment
Exhibit Hall
David Zacks, MD, PhD - 8:15 AM 10:00 AM
Poster: Retinal vascular diseases I (excluding diabetes)
C0158: Aflibercept versus bevacizumab and/or ranibizumab for recurrent macular edema secondary to central retinal vein occlusion
Exhibit Hall
Cagri Besirli, MD, PhD - 11:15 AM 1:00 PM
Poster: Inflammatory/immune responses in retinal diseases
A0203: ER-stress and mesencephalic astrocyte-derived neurotrophic factor (MANF) in an in vitro model of photoreceptors
Exhibit Hall
Mercy Pawar, Cagri Besirli, MD, PhD - 11:15 AM 1:00 PM
Poster: Inflammatory/immune responses in retinal diseases
A0206: Disheveled localizes at tight junction sites and interacts with ZO1 in BREC
Exhibit Hall
Monica Diaz-Coranguez, PhD, Cheng-mao Lin, PhD, David Antonetti, PhD - 11:15 AM 1:00 PM
Poster: Imaging Technologies and Applications I
A0263: Smartphone-based wide-field fundus photography for accurate diagnosis of pediatric retinal diseases
Exhibit Hall
Tapan Patel, MD, PhD, Tyson Kim, MD, PhD, Philip Lieu, MD, Cagri Besirli, MD, PhD, Hakan Demirci, MD, Yannis Paulus, MD
- 11:15 AM 1:00 PM
Poster: Diabetic Macular Edema Clinical Research
C0212: The Role of Midperipheral Retinal Nonperfusion in Diabetic Macular Edema
Exhibit Hall
Amro Omari, Rajesh Rao, MD, Anjali Shah, MD, Thiran Jayaundera, MD, Thomas Gardner, MD, MS - 11:15 AM 1:00 PM
Poster: Diabetic Macular Edema Clinical Research
C0193: Short-term effects of intravitreal Bevacizumab in contrast sensitivity of patients with diabetic macular edema and optimizing glycemic control
Exhibit Hall
Maria Fernanda Abalem, MBChB, PhD - 11:15 AM 11:30 AM
Paper: Novel genes found through methods old and new
Presentation: Mutations in the novel gene IFT88 are involved in causing non-syndromic inherited retinal degeneration (IRD)
Room 316C
Kari Branham, MD, CGC, John Heckenlively, MD - 11:45 AM 12:00 PM
Paper: Novel genes found through methods old and new
Presentation: Deciphering the genetic architecture of IRD by integrated analysis of 425 whole genomes
Room 316C
Kari Branham, MD, CGC, John Heckenlively, MD - 11:45 AM 12:00 PM
Paper: Impact of vision impairment
Presentation: High Prevalence of Falls, Fear of Falling and Impaired Balance in Older Adults with Vision Impairment
Room 316B
Joshua Ehrlich, MD, MPH, Brian Stagg, MD - 11:45 AM 12:00 PM
Paper: Gene function and neural protection
Presentation: Photoreceptor metabolic reprogramming provides survival advantage in acute stress while causing chronic degeneration
Room 315 Thomas Wubben, MD, PhD, Mercy Pawar, Andrew Smith, Heather Hager, MS, Cagri Besirli, MD, PhD - 12:45 PM 1:00 PM
Paper: Novel genes found through methods old and new
Presentation: Genetic Testing Adds Research and Clinical Value to a Retinal Degeneration Registry
Room 316C
Kari Branham, MS, CGC - 3:30 PM 5:15 PM
Poster: Healthcare delivery
B0335: Geographic Variation in Medicare Part D Spending on Ophthalmic Drugs
Exhibit Hall
Nathan Liles, MD, MPH, Maria Woodward, MD, MS, Paula Anne Newman-Casey, MD, MS, Lindsay Delott, MD - 3:30 PM 5:15 PM
Poster: Healthcare delivery
B0340: Perceived autonomy support from the healthcare team is associated with glaucoma medication adherence
Exhibit Hall
Paula Anne Newman-Casey, MD, MS, Leslie Niziol, Paul Lee, MD, JD - 3:30 PM 3:45 PM
Paper: Signaling in retinal degeneration
Presentation: Retinal Detachment Triggers an Innate Immune Response in the Retina
Room 315
Bing Ross, MD, PhD, Jingyu Yao, Sumathi Shanmugam, Steven Abcouwer, PhD, David Zacks, MD, PhD - 8:00 PM 10:00 PM
ARVO Classical Concert at the Hilton Hawaiian Village
Mozart: Parto! From Clemenze di Tito
Hilton Hawaiian Village 2005 Kalia Rd.
Dana Schlegel
May 3, 2018
- 8:15 AM 10:00 AM
- Poster: Lymphoma, hemangioma, surface, orbit, and eyelid tumors
Exhibit Hall
Moderator: Hakan Demirci, MD - 8:15 AM 10:00 AM
Poster: Retinal vascular diseases II (excluding diabetes)
A0113: Cilioretinal Artery Occlusion Associated with Optic Disc Edema
Exhibit Hall
Eric Weinlander, MD, Thomas Wubben, MD, PhD, Merina Thomas, MD, Katherine Davis, MD, Wayne Cornblath, MD, Mark Johnson, MD - 8:15 AM 10:00 AM
Poster: Retinal vascular diseases II (excluding diabetes)
A0121: Familial Retinal Arteriolar Tortuosity and Quantification of Vascular Tortuosity Using Swept-Source Optical Coherence Tomography Angiography
Exhibit Hall
Thao Phuong Le, MD - 8:15 AM 10:00 AM
Poster: Animal Imaging
C0139: Image-guided photomediated ultrasound therapy as a novel method to selectively treat eye vasculature
Exhibit Hall
Yannis Paulus, MD - 8:15 AM 10:00 AM
Poster: Animal Imaging
C0120: Multimodal photoacoustic microscopy, OCT, and fluorescence imaging system to detect retinal neovascularization in rabbit eyes
Exhibit Hall
Yanxiu Li, Yannis Paulus, MD - 8:15 AM 10:00 AM
Poster: Imaging: Anterior Segment
C0173: Interplicata distance as part of ciliary body biometry to understand complications of plateau iris configuration
Exhibit Hall
David Reed, Bernadete Ayres, MD, Sayoko Moroi, MD, PhD - 11:00 AM 12:45 PM
Poster: Neuroprotection
C0258: A small peptide inhibitor of the Fas receptor prevents axon degeneration and death of retinal ganglion cells in a microbead-induced mouse model of glaucoma.
Exhibit Hall
David Zacks, MD, PhD - 11:35 AM 11:50 AM
Minisymposium: Retinal lipid and glucose metabolism in health and disease
Presentation: Protein synthesis and lipid metabolism as key pathogenic processes of retinal sensibility to diabetes
Room 315
Patrice Fort, PhD, MS