Stephen A Goutman, MD, MS
Associate Professor of Neurology
Ann Arbor
MI
48109,
[email protected]

Available to mentor

Stephen A Goutman, MD, MS
Associate Professor
  • Qualifications
  • Recent Publications
  • Qualifications
    • Fellowship
      Cleveland Clinic, Neuromuscular Medicine, 2012
    • Residency
      Cleveland Clinic, Neurology, 2011
    • MS
      University of Michigan, Rackham School of Graduate Studies, Ann Arbor, 2015
    • MD
      University of Chicago Pritzker School of Medicine, 924 East 57th Street Suite 104, 2007
    • BA
      Johns Hopkins University, Baltimore, 2002
    Recent Publications See All Publications
    • Journal Article
      A randomized, placebo-controlled, double-blind phase IIb trial evaluating the safety and efficacy of tirasemtiv in patients with amyotrophic lateral sclerosis
      Bian A, Lee J, Barragan D, Andrews JA, BENEFIT-ALS Study Group , Goutman S. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2016 Mar 16; 17 (5-6): 426 - 435.
    • Journal Article
      A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis
      Cudkowicz ME, Hardiman O, Cockcroft BM, Lee JH, Malik FI, Meng L, Rudnicki SA, Wolff AA, Andrews JA, VITALITY-ALS Study Group , Goutman S. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2019 Jul 14; ((0)): 1 - 11.
    • Journal Article
      Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis
      Paganoni S, Macklin EA, Hendrix S, Berry JD, Elliott MA, Maiser S, Karam C, Caress JB, Owegi MA, Quick A, Wymer J, Goutman SA, Heitzman D, Heiman-Patterson T, Jackson CE, Quinn C, Rothstein JD, Kasarskis EJ, Katz J, Jenkins L, Ladha S, Miller TM, Scelsa SN, Vu TH, Fournier CN, Glass JD, Johnson KM, Swenson A, Goyal NA, Pattee GL, ANdres PL, Babu S, Chase M, Dagostino D, Dickson SP, Ellison N, Hall M, Hendrix K, Kittle G, McGovern M, Ostrow J, Pothier L, Randall R, Shefner JM, Sherman AV, Tustison E, Vigneswaran P, Walker J, Yu H, Chan J, Wittes J, Cohen J, Klee J, Leslie K, Tanzi RE, Gilbert W, Yeramian PD, Schoenfeld D, Cudkowicz ME. New England Journal of Medicine, 2020 Sep; 383 ((10)): 919 - 930.
    • Journal Article
      : Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial
      Goutman S, Wainger BJ, Macklin EA, Vucic S, McIlduff CE, Paganoni S, Maragakis NJ, Bedlack R, Goyal NA, Rutkove SB, Lange DJ, Rivner MH, Goutman SA, Ladha SS, Maurico EA, Baloh RH, Simmons Z, Pothier L, Kassis SB, La T, Hall M, Evora A, Klements D, Hurtado A, Pereira JD, Koh J, Celnik PA, Chaudhry V, Gable K, Juel VC, Phielipp N, Marei A, Rosenquist P, Meehan S, Oskarsson B, Lewis RA, Kaur D, Kiskinis E, Woolf CJ, Eggan K, Weiss MD, Berry JD, David WS, Davila-Perez P, Camprodon JA, Pascual-Leone A, Kiernan MC, Shefner JM, Atassi N, Cudkowicz ME. JAMA Neurology, 2021 Feb; 78 ((2)): 186 - 196.
    • Journal Article
      Effects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial
      Goutman S, Weiss MD, Macklin EA, McIlduff CE, Vucic S, Kiernan MC, Goutman S, Goyal NA, Rutkove SB, Ladha SS, Chen I-HA, Harms MB, Brannagan TH, Lacomis D, Zovlpvoc S, Ma M, Wang LH, Simmons Z, Rivner MH, Shefner JM, Cudkowicz ME, Atassi N, Mexiletine-2 ALS Study Group . Muscle and Nerve, 2021 Mar; 63 (3): 371 - 383.
    • Journal Article
      A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS
      Goutman S, Shefner JM, Andrews JA, Genge A , Jackson C , Lechtzin N , Miller TM , Cockroft BM , Meng L , Wei J , Wolff AA , Malik FI , Bodkin C , Brooks BR , Caress J , Dionne A , Fee D , Goyal NA , Hardiman O , Hayat G , Heiman-Patterson T , Heitzman D , Henderson RD , Johnston W , Karam C , Kiernan MC , Kolb SJ , Korngut L , Ladha S , Matte G , Mora JS , Needham M , Oskarsson B , Pattee GL , Pioro EP , Pulley M , Quan D , Rezania K , Schellenberg KL , Schultz D , Shoesmith C , Simmons Z , Statland J , Sultan S , Swenson A , Berg LH V D , Vu T , Vucic S , Weiss M , Whyte-Rayson A , Wymer J , Zinman L , Rudnicki SA . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2020 Sep; 22 (3-4): 287 - 299.
    • Journal Article
      Avocational exposure associations with ALS risk, survival, and phenotype: A Michigan-based case-control study.
      Goutman SA, Boss J, Jang DG, Piecuch C, Farid H, Batra M, Mukherjee B, Feldman EL, Batterman SA. J Neurol Sci, 2024 Jan 23; 457: 122899 DOI:10.1016/j.jns.2024.122899
      PMID: 38278093
    • Journal Article
      Change in peripheral immunity precede amyotrophic lateral sclerosis progression
      Murdock B, Zhao B, Raue K, Famie J, Piecuch C, Feldman EL, Zhao L, Goutman S. Journal of the Neurological Sciences, 2023 Dec; 455: 121711 DOI:10.1016/j.jns.2023.121711
    Featured News & Stories
    Department News
    New grants support six projects with 'ambitious goal’ of preventing ALS
    New grants support six projects with 'ambitious goal’ of preventing ALS
    Department News
    The ALS Association grants nearly $5M to boost clinical trial capacity and speed
    The ALS Association grants nearly $5M to boost clinical trial capacity and speed