Project Titles
- The epidemiology of sleep apnea in a bi-ethnic stroke population. (R01 HL098065)
- Sleep Apnea Health Disparities in Mexican American Stroke Patients. (R01 NS070941)
- Nocturnal rostral fluid shifts in stroke patients with sleep apnea. (R01HL123379)
- Sleep apnea after stroke: Implications for screening and treatment. (R01HL126700)
Overview
The University of Michigan Stroke Program investigates multiple aspects of post-stroke sleep apnea in patients in Corpus Christi, Texas. (1) An NHLBI-funded ancillary study assessed the frequency of sleep-disordered breathing after stroke, and the relationship of this sleep disorder to stroke outcomes. (2) The NINDS-funded sleep apnea study is designed to investigate health disparities related to sleep apnea in stroke patients. (3) An NHLBI-funded ancillary study investigates the association between nocturnal rostral fluid shifts and sleep apnea severity. (4) Finally, an NINDS-funded longitudinal, population-based study of sleep apnea and stroke outcomes is performed to improve the identification and management of important sleep apnea after stroke, provide critical data to plan future clinical trials, and explore a potential target to reduce an important ethnic health disparity.
Sleep Study Staff
Prinicipal Investigators:
Co-Investigators:
- Ronald Chervin, MD, MS
- Lewis Morgenstern, MD
- Brisa N. Sánchez, PhD
- Yan Sun, PhD, Emory University
- Joseph Burns, PhD, Michigan Technological University
Project Manager:
- Erin Case, BA
Sleep Technologist:
- Garnett L. Hegeman, III, RPSGT
Corpus Christi Field Office Staff:
- Nelda Garcia, Field Office Director
- Pamela Arevalo
- Leslie Garcia
- April Medina
- Celso "Marty" Toscano
- Andrew Valverde
Consultants:
- T. Douglas Bradley, MD, University of Toronto
- Virend Somers, MD, PhD, Mayo Clinic
- Azadeh Yadollahi, PhD, University of Toronto
Publications:
Lisabeth LD, Sánchez BN, Chervin RD, Morgenstern LB, Zahuranec DB, Tower SD, Brown DL. High Prevalence of Post-Stroke Sleep Disordered Breathing in Mexican Americans. Sleep Med, in press.
Brown DL, Mowla A, McDermott M, Morgenstern LB, Hegeman G 3rd, Smith MA, Garcia NM, Chervin RD, Lisabeth LD. Ischemic Stroke Subtype and Presence of Sleep-Disordered Breathing: The BASIC Sleep Apnea Study. J Stroke Cerebrovasc Dis 2015; 24: 388-393.
De Lott LB, Lisabeth LD, Sánchez BN, Morgenstern LB, Smith MA, Garcia NM, Chervin RD, Brown DL. Prevalence of pre-stroke sleep apnea risk and short or long sleep duration in a bi-ethnic stroke population.Sleep Med 2014; 15: 1582-1585.
Brown DL, McDermott M, Mowla A, De Lott L, Morgenstern LB, Kerber KA, Hegeman G 3rd, Smith MA, Garcia NM, Chervin RD, Lisabeth LD. Brainstem infarction and sleep-disordered breathing in the BASIC sleep apnea study. Sleep Med 2014; 15: 887-91.
Brown DL, Chervin RD, Hegeman G 3rd, Smith MA, Garcia NM, Morgenstern LB, Lisabeth LD. Is technologist review of raw data necessary after home studies for sleep apnea? J Clin Sleep Med2014;10:371-375.
Reeves SL, Brown DL, Chervin RD, Morgenstern LB, Smith MA, Lisabeth LD. Agreement between stroke patients and family members for ascertaining pre-stroke risk for sleep apnea. Sleep Med 2014;15:121-124.
Kerber KA, Brown DL, Skolarus LE, Morgenstern LB, Smith MA, Garcia NM, Lisabeth LD. Validation of the 12-Item Stroke-Specific Quality of Life Scale in a Bi-ethnic Stroke Population. J Stroke Cerebrovasc Dis2013; 22: 1270-1272.
