Lisa M Sharkey
Research Assistant Professor
Neurology
[email protected]

Available to mentor
Lisa M Sharkey
Research Assistant Professor
  • Recent Publications
    • Recent Publications See All Publications
    • Presentation
      From Mutations to Mechanisms: UBQLN2's Role in Protein Quality Control and Neurodegenerative Disease
      Sharkey L. 2023 Dec 5;
    • Journal Article
      Ubiquilin-2 regulates pathological alpha-synuclein.
      Sandoval-Pistorius SS, Gerson JE, Liggans N, Ryou JH, Oak K, Li X, Negron-Rios KY, Fischer S, Barsh H, Crowley EV, Skinner ME, Sharkey LM, Barmada SJ, Paulson HL. Sci Rep, 2023 Jan 6; 13 (1): 293 DOI:10.1038/s41598-022-26899-0
      PMID: 36609661
    • Journal Article
      Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils.
      Desai AA, Zupancic JM, Trzeciakiewicz H, Gerson JE, DuBois KN, Skinner ME, Sharkey LM, McArthur N, Ferris SP, Bhatt NN, Makowski EK, Smith MD, Chen H, Huang J, Jerez C, Kane RS, Kanaan NM, Paulson HL, Tessier PM. bioRxiv, 2023 Jul 4; DOI:10.1101/2023.07.04.547698
      PMID: 37461643
    • Journal Article
      Wild-type and pathogenic forms of ubiquilin 2 differentially modulate components of the autophagy-lysosome pathways.
      Idera A, Sharkey LM, Kurauchi Y, Kadoyama K, Paulson HL, Katsuki H, Seki T. J Pharmacol Sci, 2023 Jul; 152 (3): 182 - 192. DOI:10.1016/j.jphs.2023.05.002
      PMID: 37257946
    • Presentation
      Ubiquilin2’s role in neuronal protein quality control pathways
      Sharkey L. 2023 May 3;
    • Presentation
      Uncovering critical roles for retrotransposon-derived proteins in Ubiquilin-2 (UBQLN2) biology; implications for ALS research
      Sharkey L. 2023 May 12;
    • Presentation
      Uncovering critical roles for retrotransposon-derived proteins in Ubiquilin-2 (UBQLN2) biology; implications for ALS research
      Sharkey L. 2023 Apr 7;
    • Journal Article
      Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration.
      Benyair R, Giridharan SSP, Rivero-Ríos P, Hasegawa J, Bristow E, Eskelinen E-L, Shmueli MD, Fishbain-Yoskovitz V, Merbl Y, Sharkey LM, Paulson HL, Hanson PI, Patnaik S, Al-Ramahi I, Botas J, Marugan J, Weisman LS. Autophagy Rep, 2023 2 (1): DOI:10.1080/27694127.2023.2166722
      PMID: 37064812