Stephanie Eid, PhD, photo

Stephanie Eid, PhD

Frances and Kenneth Eisenberg Emerging Scholar
Research Assistant Professor
Department of Neurology
5017 BSRB
Ann Arbor MI 48109-2200

Understanding the role of Schwann cells in prediabetic and diabetic neuropathy

Dr. Stephanie Eid has served as a diabetes team leader for the NeuroNetwork for Emerging Therapies since January 2019. Her current efforts are focused on exploring how Schwann cells, the supporting cells of peripheral nerves, maintain the health of nerve axons (thread-like structures attached to a nerve cell and send out signals) under normal conditions and promote damage in prediabetic and diabetic neuropathy. She is particularly interested in the role of extracellular vesicles and miRNAs in regulating nerve metabolism and function with or without exercise and dietary interventions. These innovative studies will advance our understanding of prediabetic and diabetic neuropathy and help develop novel Schwann cell-specific targets for neuropathy treatment.


  • BS/MS, Physiology, American University of Beirut, 2012
  • PhD, Neuroscience, American University of Beirut/Paris Descartes University, Sorbonne Paris Cité, 2017

Honors & Awards

  • Wolfe Neuropathy Research Prize, American Neurological Association
  • The Angelika Bierhaus Prize in basic research, Neurodiab (diabetic neuropathy study group of the European Association for the Study of Diabetes)  
  • National Council for Scientific Research – Lebanon Fellowship
  • Training Scholarship, Paris Descartes University
  • Travel grant, Peripheral Nerve Society
  • Travel grant, National Institute of Diabetes and Digestive and Kidney Diseases

Top Publications

Eid SA, Feldman EL. Advances in Diet-Induced Rodent Models of Metabolically Acquired Peripheral Neuropathy. Dis Model Mech. In press

Eid S*, Hinder LM*, Zhang H*, Eksi R, Nair V, Eddy S, Eichinger F, Park M, Saha J, Berthier CC, Jagadish HV, Guan Y, Pennathur S, Hur J, Kretzler M, Feldman EL, Brosius FC. Gene expression profiles of diabetic kidney disease and neuropathy in eNOS knockout mice: predictors of pathology and RAAS blockade effects. FASEB J. 35(5):e21467, 2021.  
*The authors contributed equally to this work

Eid S*, Guo K*, Elzinga SE*, Pacut C, Feldman EL, and Hur J. Genome-Wide Profiling of DNA Methylation and Gene Expression Identifies Candidate Genes of Human Diabetic Neuropathy.  Clin Epigenet. 2020, 12, 123.
*The authors contributed equally to this work

Eid SA, El Massry M, Hichor M, Haddad M, Grenier J, Dia B, Barakat R, Boutary S, Chanal J, Aractingi S, Wiesel P, Szyndralewiez C, Azar ST, Boitard C, Zaatari G, Eid AA*, Massaad C*. Targeting the NADPH Oxidase-4 and Liver X Receptor Pathway Preserves Schwann Cell Integrity in Diabetic Mice. Diabetes. 2020, 69(3): 448-464.
Eid SA*, O'Brien PD*, Guo K*, Rumora AE*, Hinder LM*, Hayes JM, Mendelson FE, Hur J, Feldman EL. Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes. Dis Model Mech. 2020, 13(2).
*The authors contributed equally to this work