2020 - 2021 Collaboratory Archive

Thursday, June 24, 2021: LHS Collaboratory Summer Workshop: Learning Health Systems 101

This virtual workshop will review the basic concepts behind Learning Health Systems including the learning cycle, infrastructure, and learning communities.  Participants will engage in a collaborative activity to design a learning cycle.  Registration for this event is limited. Please consider registering early.

Charles P. Friedman, PhD, Department Chair of Learning Health Sciences, Josiah Macy Jr. Professor of Medical Education

Professor Friedman's presentation slides  

Thursday, March 25, 2021: The Swiss Learning Health System (SLHS): A National Initiative to Support Evidence Uptake in Policy and Practice

Dr. Boes and Dr. Mantwill will provide an overview of the SLHS and its key features, as well as its capacity-building efforts to train young researchers in the field of learning health systems, and the development of a centralized metadata repository in support of creating a sufficient large evidence basis to support learning cycles in the Swiss health system. Further, they will discuss lessons learned from the past and the newest developments of the SLHS in light of a second funding phase supported by the Swiss government.

Promoting and supporting the uptake of evidence and evidence-informed decision-making in health-systems related policy and practice is a challenge. In Switzerland, the need to address this matter has been increasingly emphasized by different actors in the health system. In particular, the lack of comprehensive coordination efforts in the field of health services research, and subsequent knowledge translation activities, has been stressed.

In response, the Swiss Learning Health System (SLHS) was established as a nationwide project in 2017, currently involving ten academic partner institutions. One of the overarching objectives of the SLHS is to bridge research, policy, and practice by providing an infrastructure that supports learning cycles by: continuously identifying issues relevant to the Swiss health system, systemizing relevant evidence, presenting potential courses of action, and revising and reshaping responses.

Key features of learning cycles in the SLHS include the development of policy/evidence briefs that serve as a basis for stakeholder dialogues with actors from research, policy, and practice. Issues that are identified to be further pursued are monitored for potential implementation and eventually evaluated to inform new learning cycles and to support continuous learning within the system.

Stefan Boes, PhD, MSc , Vice Principal-Department of Health Sciences and Medicine, Professor of Health Economics

Sarah Mantwill, PhD, Research Manager and Coordinator, Swiss Learning Health System (SLHS), University of Lucerne

Professor Boes' and Dr. Mantwill's presentation slides

Tuesday, February 23, 2021: Digital Transformation in Healthcare for a Diverse World

Keynote speaker:

Bernardo Mariano, Jr., Director of Digital Health & Innovation, Chief Information Officer (CIO), World Health Organization (WHO)

Topic: WHO's Global Strategy on Digital Health as an Enabler to Achieving SDG 3

Mr. Mariano's presentation slides


Laurie McCauley, DDS, MS, PhD, Dean, William K and Mary Anne Najjar Professor of Periodontics, University of Michigan School of Dentistry

Breakout Session #1 LHS and Pain

Alex F. DaSilva, DDS, DMedSc, Associate Professor, Department of Biologic & Materials Sciences, Director, Learning Health Systems, University of Michigan School of Dentistry

Topic: Integrating Diverse Health Ecosystems for Optimal Pain Treatment, Education, and Research

Dr. DaSilva's presentation slides

Ivo Dinov, Ph.D., Professor of Computational Medicine and Bioinformatics, Medical School,Associate Director for Education and Training, Michigan Institute for Data Science (MIDAS),
Vice Chair, Department of Health Behavior and Biological Sciences, University of Michigan

Perspective: Data De‐Identification and Clinical Decision Support

Dr. Dinov's presentation slides 

Breakout Session #2 LHS and Caries Risk

Margherita Fontana, DDS, PhD, Clifford Nelson Endowed Professor and Professor of Dentistry, University of Michigan School of Dentistry

Topic: Caries Risk Prediction Models

Dr. Fontana's presentation slides

Alonso Carrasco-Labra, DDS, MSc, PhD, Senior Director, Department of Evidence Synthesis and Translation Research, American Dental Association, Science and Research Institute, LLC, Adjunct Assistant Professor, Department of Oral and Craniofacial Health Science, School of Dentistry, University of North Carolina at Chapel Hill

Perspective: LHS and Evidence-based Clinical Practice

Dr. Alonso Carrasco-Labra's presentation slides

Breakout Session #3 LHS and Opioids

Romesh Nalliah, BDS, MHCM, Associate Dean for Patient Services and Clinical Professor of Dentistry, University of Michigan School of Dentistry

Topic: Iteratively Learning about Dental Opioid Prescribing

Dr. Nalliah's presentation slides

Chad Brummett, MD, Bert N. LaDu Professor of Anesthesiology, Senior Associate Chair, Research, Co-Director of the Michigan Opioid Prescribing Engagement Network (Michigan OPEN)
University of Michigan

Perspective: Precision Health in Opioid Management

Dr. Brummett's presentation slides

Thursday, January 21, 2021: Data Standards and Learning Health Systems–Challenges and Opportunities


Event Slides

Learning Health Systems thrive with use of real-world data from electronic health record (EHR) systems in both observational and interventional research to generate real-world evidence. Standardized EHR data can enable the aggregation of data and the generation of real-world evidence that will inform care delivery and improve patient outcomes. Data standards can also increase the speed in which promising evidence-based interventions are disseminated and adopted into new settings. However, despite their great potential, data standards have proven to be difficult and costly to implement, and nationally standardized EHR data continues to elude us.

Speaker: Rachel Richesson, PhD, MPH, MS, FACMI, Professor of Learning Health Sciences

Thursday, November 12, 2020: Reflections on Learning to Improve: Foundational Ideas, Observations from Practice, and Building a Field


Dr. Bryk’s talk describes a set of normative challenges that confront us, including ways to shift from pursuing the hot new idea as the silver bullet to continuously improving how core processes and systems in educational institutions work. It is a distinct form of inquiry that values basic research knowledge and rigorous evidence about new programs and interventions, but that also sees efforts aiming to solve problems of practice reliably and at scale as generating its own form of generalizable knowledge. It transforms the core improvement question from “What Works” into “What Works for Whom and under What Set of Context Conditions.”


Anthony S. Bryk, President of the Carnegie Foundation for the Advancement of Teaching


Donald J. Peurach, PhD, Professor, University of Michigan School of Education; Senior Fellow, Carnegie Foundation for the Advancement of Teaching


Elizabeth Birr Moje, PhD, Dean, George Herbert Mead Collegiate Professor of Education, and Arthur F. Thurnau Professor School of Education; Faculty Associate in the Institute for Social Research; Latino/a Studies; and the Joint Program in English & Education, University of Michigan

Caren M. Stalburg, MD, MA, Collaborative Lead for Education; Associate Professor of Learning Health Sciences

Tuesday, October 20, 2020: LHS as a Driver of Diversity, Equity, and Inclusion

Event Slides

The October 2020 LHS Collaboratory shared lessons from health advocates working on the frontlines to make healthcare and health more equitable. These thought leaders and do-ers illuminated the transformative power of LHSs - and the diverse and inclusive communities of interest that are collaborating to realize them.


Joshua C. Rubin, J.D., M.B.A., M.P.P., M.P.H., Program Officer, Learning Health System Initiatives


Luis Belén, Chief Executive Officer of the National Health IT Collaborative for the Underserved (NHIT Collaborative)

Danielle Brooks, J.D., Director of Health Equity, Amerihealth Caritas

Melissa S. Creary, Ph.D., M.P.H., Assistant Professor, Department of Health Management and Policy School of Public Health

Thursday, September 17, 2020: Seminar Series Fall Symposium Kick-Off - Academic Medical Centers as Learning Health Systems

The Collaboratory's fall symposium event showcased the LHS experiences of three research-intensive academic centers that have been promoting LHS methods.  Distinguished senior colleagues from Duke, Vanderbilt, and Washington University, described and discussed their institutions' work in this area.  They discussed strategies employed, investments made, challenges encountered, and successes achieved.


Carol R. Bradford, M.D., M.S., Leslie H. and Abigail S. Wexner Dean's Chair in Medicine, Ohio State University


Kevin B. Johnson, M.D., M.S., F.A.A.P., F.A.C.M.I., Cornelius Vanderbilt Professor & Chair, Department of Biomedical Informatics Professor; Department of Pediatrics Informatician-in-Chief, Vanderbilt University Medical Center

Christopher J. Lindsell, Ph.D., Professor of Biostatistics, Vanderbilt University; Co-director of the HEAlth Data Science, (HEADS) Center, Vanderbilt University

Philip R. O. Payne, Ph.D., F.A.C.M.I., F.A.M.I.A., Janet and Bernard Becker Professor and Director, Institute for Informatics (I2); Associate Dean for Health Information and Data Science, Chief Data Scientist, Washington University School of Medicine

Michael Pencina, Ph.D., Professor of Biostatistics and Bioinformatics, Duke University; Vice Dean for Data Science and Information Technology, Duke University

Eric G. Poon, M.D., M.P.H., Professor of Medicine, Chief Health Information Officer, Duke University