Duncan Laboratory Publications

Thomas, P.V., Cheng, A.L., Colby, C.C., Liu, L., Patel, C.K., Josephs, L., Duncan, R.K. (2014) Localization and proteomic characterization of cholesterol-rich membrane microdomains in the inner ear, Journal of Proteomics,103:178-193.

Scholl, E.S., Pirone, A., Cox, D.H., Duncan, R.K., Jacob, M.H. (2014) Alternative splice isoforms of small conductance calcium-activated SK2 channels differ in molecular interactions and surface levels, Channels (Austin), 8(1):62-75

Purcell, E.K., Yang, A., Liu, L., Velkey, J.M., Morales, M.M., Duncan, R.K. (2013) BDNF profoundly and specifically increases KCNQ4 expression in neurons derived from embryonic stem cells, Stem Cell Research, 10:29-35.

Crumling, M.A., Liu, L.Q., Thomas, P.V., Benson, J., Kanicki, A., Dolan, D., Duncan, R.K. (2012) Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclodextrin, PLoS One, 7:e53280.

Purcell, E.K., Naim, Y., Yang, A., Leach, M.K., Velkey, J.M., Duncan, R.K., Corey, J.M. (2012) Combining topographical and genetic cues to promote neuronal fate specification in stem cells, Biomacromolecules, 13:3427-3438.

Hill, G.W., Purcell, E.K., Velkey, J.M., O’Shea, K.S., Altschuler, R.A., Duncan, R.K. (2012) Netrin-1 mediated axon guidance in murine embryonic stem cell-derived neuron, Stem Cells and Development, 21:2827-2837.

Purcell, E.K., Liu, L., Thomas, P.V., Duncan, R.K. (2011) Cholesterol influences voltage-gated calcium channels and BK-type potassium channels in auditory hair cells.  PLoS One, 6:e26289.  PMCID:PMC3194812

Tong, M.T., Hernandez, J.L., Purcell, E.K.., Altschuler, R.A., Duncan, R.K. (2010) The intrinsic electrophysiological properties of neurons derived from mouse embryonic stem cells overexpressing neurogenin-1. American Journal of Physiology-Cell Physiology, 299:C1335-1344.  PMCID: PMC3006329

Kim, J.-M., Beyer, R., Morales, M.M., Chen, S., Liu, L., Duncan, R.K. (2010) Expression of BK-type calcium-activated potassium channel splice variants during chick cochlear development, Journal of Comparative Neurology, 518:2554-2569.  PMCID:PMC20503427

Li, Y., Atkin, G., Liu, L., Morales, M., Tong, M., Duncan, R.K, (2009) Developmental expression of BK channels in chick cochlear hair cells. BMC Developmental Biology, 9:67-73.  PMCID: PMC2803478

Sokolowski, B.*, Duncan, R.K.*, Chen, S., Karolat, J., Kathiresan, T., Harvey, M. (2009) The large-conductance Ca(2+)-activated K(+) channel interacts with the apolipoprotein ApoA1. Biochemical and Biophysical Research Communications, 387:671-675. (*, equal contribution)  PMCID: PMC2757790

Tong, M., Duncan, R.K. (2009) Tamoxifen inhibits BK channels in chick cochlea without alterations in voltage-dependent activation. American Journal of Physiology-Cell Physiology, 297:C75-85.  PMCID: PMC2711652

Crumling, M.A., Tong, M., Aschenbach, K.L., Liu, L.Q., Pipitone, C.M., Duncan, R.K. (2009) P2X antagonists inhibit styryl dye entry into hair cells. Neuroscience, 161:1144-1153.  PMCID: PMC2846836

Mustapha-Chaib, M., Fang, Q.,Gong, T.W.,  Dolan, D., Raphael, Y., Camper, S.A., Duncan, R.K. (2009) Deafness and permanently reduced potassium channel gene expression and function in hypothyroid Pit1dw mutants. Journal of Neuroscience, 29:1212-1223.  PMCID: PMC – In Process

Holt, A.G., Asako, M., Duncan, R.K., Lomax, C.A., Juiz, J., Altschuler, R.A. (2006) Deafness associated changes in expression of two-pore domain potassium channels in the rat cochlear nucleus. Hearing Research, 216-217:146-153.

Duncan, R.K. (2005) Tamoxifen alters gating of the BK α subunit and mediates enhanced interactions with the avian β subunit. Biochemical Pharmacology, 70(1):47-58.

Matthews, T.M., Duncan, R.K., Zidanic, M., Fuchs, P.A. (2005) Cloning and characterization of SK2 channel from chicken short hair cells. Journal of Comparative Physiology A, 191:491-503.

Duncan, R.K., Fuchs, P.A. (2003) Variation in large-conductance, calcium-activated potassium channels from hair cells along the chicken basilar papilla.  Journal of Physiology, 547:357-371.

Duncan, R.K., Ile, K.E., Dubin, M.D., Saunders, J.C. (2001) Contours of hair cell hair bundles along the chick basilar papilla.  Journal of Anatomy, 198:103-116.

Duncan, R.K., Saunders, J.C. (2000) Stereocilium injury mediates hair bundle stiffness loss and recovery following intense water-jet stimulation.  Journal of Comparative Physiology A, 186:1095-1106.

Duncan, R.K., Eisen, M.D., Saunders, J.C. (1999) Distal separation of chick cochlear hair cell stereocilia: analysis of contact constraint models. Hearing Research, 127:22-30.

Eisen, M.D., Duncan, R.K., Saunders, J.C. (1999) The tip link's role in asymmetric stereocilia motion of chick cochlear hair cells. Hearing Research, 127:14-21.

Duncan, R.K., Dyce, O.H., Saunders, J.C. (1998) Low calcium abolishes tip-links and alters relative stereocilia motion in chick cochlear hair cells. Hearing Research, 124:69-77.

Duncan, R.K., Grant, J.W. (1997) A finite-element model of inner ear hair bundle micromechanics. Hearing Research, 104:15-26.

Duncan, R.K., Hernandez, H.N., Saunders, J.C. (1995) Relative stereocilia motion of chick cochlear hair cells during high-frequency water-jet stimulation. Auditory Neuroscience, 1:321-329.

Tang, B., Mommaerts, J., Duncan, R.K., Duke, J.C., Jr., Dillard, D.A. (1993) Nondestructive evaluation of model adhesive joints by PVDF piezoelectric film sensors. Experimental Mechanics, 33:102-109.