Publications

Highlights

The Dual Role of CD6 as a Therapeutic Target in Cancer and Autoimmune Disease
Gurrea-Rubio M, Fox DA. Frontiers in Medicine. October 5, 2022 

Senescent Cells Accumulate in Systemic Sclerosis Skin
Shi B, Tsou PS, Ma F, Mariani MP, Mattichak MN, LeBrasseur NK, Chini EN, Lafyatis R, Khanna D, Whitfield ML, Gudjonsson JE, Varga J. Journal of Investigative Dermatology. September 30, 2022 

Systemic Sclerosis Associated Interstitial Lung Disease: A Conceptual Framework for Subclinical, Clinical, and Progressive Disease
Roofeh D, Brown KK, Kazerooni EA, Tashkin D, Assassi S, Martinez F, Wells AU, Raghu G, Denton CP, Chung L, Hoffmann-Vold AM, Distler O, Johannson KA, Allanore Y, Matteson EL, Kawano-Dourado L, Pauling JD, Seibold JR, Volkmann ER, Walsh SLF, Oddis CV, White ES, Barratt SL, Bernstein EJ, Domsic RT, Dellaripa PF, Conway R, Rosas I, Bhatt N, Hsu V, Ingegnoli F, Kahaleh B, Garcha P, Gupta N, Khanna S, Korsten P, Lin C, Mathai SC, Strand V, Doyle TJ, Steen V, Zoz DF, Ovalles-Bonilla J, Rodriguez-Pinto I, Shenoy PD, Lewandoski A, Belloli E, Lescoat A, Nagaraja V, Ye W, Huang S, Maher T, Khanna D. Rheumatology. September 29, 2022

Deficiency of Inhibitory TLR4 Homolog RP105 Exacerbates Fibrosis
Wang W, Bale S, Yalavarthi B, Verma P, Tsou PS, Calderone KM, Bhattacharyya D, Fisher GJ, Varga J, Bhattacharyya S. JCI Insight. September 22, 2022 

Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis
Sapao P, Roberson EDO, Shi B, Assassi S, Skaug B, Lee F, Naba A, White BEP, Córdova-Fletes C, Tsou PS, Sawalha AH, Gudjonsson JE, Ma F, Verma P, Bhattacharyya D, Carns M, Strauss JF 3rd, Sicard D, Tschumperlin DJ, Champer MI, Campagnola PJ, Teves ME, Varga J. Journal of Investigative Dermatology. September 15, 2022 

Tofacitinib Blocks IFN-Regulated Biomarker Genes in Skin Fibroblasts and Keratinocytes in a Systemic Sclerosis Trial
Khanna D, Padilla C, Tsoi LC, Nagaraja V, Khanna PP, Tabib T, Kahlenberg JM, Young A, Huang S, Gudjonsson JE, Fox DA, Lafyatis R. JCI Insight. August 9, 2022 

Differences in Symptom Experience Among Patients with Systemic Sclerosis: A Cluster Analytic Approach to Identifying Subgroups
Murphy SL, Chen YT, Lee YC, Carns M, Aren K, Korman B, Hinchcliff M, Varga J. Rheumatology. August 3, 2022 

Inhibition of Bromodomain Extraterminal Histone Readers Alleviates Skin Fibrosis in Experimental Models of Scleroderma
Vichaikul S, Gurrea-Rubio M, Amin MA, Campbell PL, Wu Q, Mattichak MN, Brodie WD, Palisoc PJ, Ali M, Muraoka S, Ruth JH, Model EN, Rohraff DM, Hervoso JL, Mao-Draayer Y, Fox DA, Khanna D, Sawalha AH, Tsou PS. JCI Insight. March 29, 2022

Functional Characterization of Glycoprotein Nonmetastatic Melanoma Protein B in Scleroderma Fibrosis
Palisoc PJ, Vaikutis L, Gurrea-Rubio M, Model EN, O'mara MM, Ory S, Vichaikul S, Khanna D, Tsou PS, Sawalha AH. Frontiers in Immunology. February 24, 2022 

Rehabilitation Interventions in Systemic Sclerosis: A Systematic Review and Future Directions
Murphy S, Poole J, Chen Y, Lescoat A, Khanna D. Arthritis Care & Research. January 2022 

Outcome Measurement Instrument Selection for Lung Physiology in Systemic Sclerosis Associated Interstitial Lung Disease: A Systematic Review Using the OMERACT Filter 2.1 Process
Roofeh D, Barratt SL, Wells AU, Kawano-Dourado L, Tashkin D, Strand V, Seibold J, Proudman S, Brown KK, Dellaripa PF, Doyle T, Leonard T, Matteson EL, Oddis CV, Solomon JJ, Sparks JA, Vassallo R, Maxwell L, Beaton D, Christensen R, Townsend W, Khanna D. Seminars in Arthritis and Rheumatism. December 2021

Intensive and App-Delivered Occupational Therapy to Improve Upper Extremity Function in Early Diffuse Cutaneous Systemic Sclerosis: A Pilot Two-Arm Trial
Murphy SL, Barber M, Huang S, Sabbagh M, Cutter G, Khanna D. Rheumatology. November 2021 

Advances in Epigenetics in Systemic Sclerosis: Molecular Mechanisms and Therapeutic Potential
Tsou PS, Varga J, O'Reilly S. Nature Reviews Rheumatology. September 3, 2021

Faculty Publications

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