Sundeep Kalantry, Ph.D.

Professor of Human Genetics

3710-D Med Sci II SPC 5618
1241 E. Catherine St.
Ann Arbor, MI 48109-5618


Areas of Interest

Epigenetics, X-chromosome inactivation, stem cell biology.

Honors & Awards

  • 2012-2014 March of Dimes Basil O'Connor Starter Scholar Research Award
  • 2011-2016 NIH Director's New Innovator Award
  • 2011-2015 Ellison Medical Foundation New Scholar in Aging
  • 2009 Biological Sciences Scholar, University of Michigan
  • 2007-12 NIH Pathway to Independence Award (K99/R00)
  • 2003-06 American Cancer Society Postdoctoral Fellowship
  • 2001 Julian R. Rachele Prize, Weill Graduate School of Medical Sciences of Cornell University


  • 2002-2009 Postdoctoral Fellowship, University of North Carolina, Chapel Hill
  • 1995-2001 Ph.D., Cell Biology and Genetics/Molecular Biology, Weill Graduate School of Medical Sciences of Cornell University, New York, NY
  • 1989-93 B.A., Biochemistry, Cornell University, Ithaca, NY

Published Articles or Reviews

Harris C, Cloutier M, Trotter M, Hinten M, Gayen S, Du Z, Xie W, Kalantry S. Conversion of Random X-inactivation to Imprinted X-inactivation by Maternal PRC2. eLife, 2019. Harris, Cloutier et al., 2019.pdf

Cloutier M, Harris C, Gayen S, Maclary E, Kalantry S. Experimental Analysis of Imprinted Mouse X-Chromosome Inactivation. Methods in Molecular Biology, 2018. Cloutier et al., 2018.pdf

Gayen S, Maclary E, Murata-Nakamura Y, Vallianatos CN, Porter RS, Garay PM, Iwase S, and Kalantry S. Induction of X-chromosome inactivation by the Histone Demethylase SMCX/KDM5C. bioRxiv, 2017. Gayen et al., 2017b.pdf

Gayen S, Kalantry S. Chromatin-enriched lncRNAs: a novel class of enhancer RNAs. Nature Structural & Molecular Biology, 2017. Gayen et al., 2017.pdf

Maclary E, Hinten M, Harris C, Sethuraman S, Gayen S, Kalantry S. PRC2 represses transcribed genes on the imprinted inactive X chromosome in mice. Genome Biology, 2017. Maclary et al., 2017.pdf

Huisman B, Manske G, Carney S, Kalantry S. Functional Dissection of the m6A RNA Modification. Trends in Biochemical Sciences, 2017. Huisman et al., 2016.pdf

Zhang H, Gayen S, Xiong J, Zhou B, Shanmugam AK, Sun Y, Rao RC, Wang S, Nesvizhskii AI, Kalantry S, Dou Y. MLL1 Inhibition reprograms embryonic and epiblast stem cells to naïve pluripotency via altered histone H3 K4 methylation. Cell Stem Cell 2016 April 7;18 (4):481-494. PubMed PMID 26996599; PubMed Central PMCID PMC4826731. Zhang et al., 2016.pdf

Gayen S, Maclary E, Buttigieg E, Hinten M, Kalantry S. A Primary role for the Tsix lncRNA in maintaining random X-chromosome inactivation. Cell Reports 2015 May 26;11(8):1251-65. PubMed PMID: 25981039; PubMed Central PMCID: PMC4449283. Gayen et al., 2016.pdf

Hinten M, Maclary E, Gayen S, Harris C, and Kalantry S. Visualizing Long Non-coding RNAs on Chromatin. Methods in Molecular Biology, 1402: 147-64, 2016. PubMed PMID: 26721489; PubMed Central PMCID: PMC5094191.. Hinten et al., 2016.pdf

Taniguchi K, Townshend RF, Freddo AM, Prakash A, Gayen S, Harris CE, Tsai Y-H, DeLong CJ, Chue DJ, Lopez SA, Spence JR, O’Shea KS, Margolis B, Kalantry S, and Gumucio DL. Pluripotent Stem Cells: An Improved Model of Lumen Formation. Stem Cell Reports 5:954-962, 2015. Taniguchi et al., 2015.pdf

Kalantry S and Mueller. Mary Lyon: A Tribute. American Journal of Human Genetics,97(4):507-511, 2015. Kalantry & Mueller, 2015.pdf

Ku C-J, Lim K-C, Kalantry S, Maillard I, Engel JD, and Tomonori H. A mono- to biallelic T cell transcriptional switch regulates GATA3 abundance. Genes & Development, 29(18):1930-41, 2015. Ku et al., 2015.pdf

Sarkar MK, Gayen S, Kumar S, Maclary E, Buttigieg E, Hinten M, Kumari A, Harris C, Sado T, Kalantry S. An Xist-activating antisense RNA required for X-chromosome inactivation. Nature Communications 2015 Oct 19;6:8564. PubMed PMID: 26477563; PubMed Central PMCID: PMC4616153. Sarkar et al., 2015.pdf

Kang, J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Surani MA, Koralov SB, Kalantry S, Chavez L, and Rao A. Simultaneous deletion of Tet1 and Tet3 increases transcriptional variability in early embryogenesis. PNAS, 112(31):E4236-45, 2015. Kang et al., 2015.pdf

Gayen S, Maclary E, Hinten M, Kalantry S. Sex-specific silencing of X-linked genes by the Xist RNA. Proceedings of the National Academy of Sciences of the U.S.A. 2016 Jan 19;113(3):E309-18. PubMed PMID: 26739568; PubMed Central PMCID: PMC4725534. Gayen et al., 2015.pdf

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