Frederick Korley, MD, PhD

Frederick Korley, M.D., Ph.D. is a Professor of Emergency Medicine at the University of Michigan. He completed his medical degree and residency training in emergency medicine at the Northwestern University where he served as chief resident. He subsequently completed a doctoral degree in clinical investigation at the Johns Hopkins University Bloomberg School of Public Health and was elected to Phi Beta Kappa. He was formerly on faculty at Johns Hopkins University as the inaugural recipient of Robert E. Meyerhoff Endowed Professorship.

His research work is focused on the development of novel diagnostics and therapeutics for traumatic brain injury (TBI). With regards to the development of novel diagnostics, Dr. Korley has two patents for biofluid-based biomarkers for brain injury detection and outcome prognostication. In collaboration with colleagues in engineering, Dr. Korley is developing a credit card-sized microfluidic device for point-of-care measurement of TBI biofluid biomarkers. He is also a national principal investigator of two federally funded multi-center research studies that are investigating the use of biofluid-based biomarkers for 1) subject selection in clinical trials; 2) monitoring individual patient response to promising neuroprotective agents. With regards to the development of therapeutics for TBI, Dr. Korley is a principal investigator of an NINDS funded phase II adaptive design clinical trial that is investigating the optimal treatment parameters of hyperbaric oxygen that is most likely to demonstrate improvement in the rate of good neurological outcome versus control in a subsequent confirmatory trial. During the ongoing COVID-19 pandemic, Dr. Korley is leveraging his expertise in the testing of novel therapeutics to lead an NHLBI-funded multi-center clinical trial of COVID-19 convalescent plasma in outpatients (C3PO) as one of the national co-PIs. He is a member of the NINDS Neurological Sciences and Disorders A (NSD-A) study section and the National Academies of Sciences, Engineering and Medicine’s Committee on Accelerating Progress in Traumatic Brain Injury Research and Care. Dr. Korley is the recipient of the 2021 Society of Academic Emergency Medicine (SAEM) Mid-Career Investigator Award.