Assistant Research Scientist
Dermatology
[email protected]
Available to mentor
Mrinal K Sarkar
Assistant Research Scientist
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Jiang Y, Gruszka D, Zeng C, Swindell WR, Gaskill C, Sorensen C, Brown W, Gangwar RS, Tsoi LC, Webster J, Sigurdardottir SL, Sarkar MK, Uppala R, Kidder A, Xing X, Plazyo O, Xing E, Billi AC, Maverakis E, Kahlenberg JM, Gudjonsson J, Ward NL. JCI Insight, 2024 Mar 12;Journal ArticleSuppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling.
DOI:10.1172/jci.insight.172764 PMID: 38470486 -
Yu Z, Vieyra-Garcia P, Benezeder T, Crouch JD, Kim IR, O'Malley JT, Devlin PM, Gehad A, Zhan Q, Gudjonsson JE, Sarkar MK, Kahlenberg JM, Gerard N, Teague JE, Kupper TS, LeBoeuf NR, Larocca C, Tawa M, Pomahac B, Talbot SG, Orgill DP, Wolf P, Clark RA. J Invest Dermatol, 2024 Mar; 144 (3): 621 - 632.e1.Journal ArticlePhototherapy Restores Deficient Type I IFN Production and Enhances Antitumor Responses in Mycosis Fungoides.
DOI:10.1016/j.jid.2023.06.212 PMID: 37716650 -
Uppala R, Sarkar MK, Young KZ, Ma F, Vemulapalli P, Wasikowski R, Plazyo O, Swindell WR, Maverakis E, Gharaee-Kermani M, Billi AC, Tsoi LC, Kahlenberg JM, Gudjonsson JE. iScience, 2024 Feb 16; 27 (2): 108986Journal ArticleHERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling.
DOI:10.1016/j.isci.2024.108986 PMID: 38327798 -
van Straalen KR, Ma F, Tsou P-S, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. J Clin Invest, 2024 Feb 1; 134 (3):Journal ArticleSingle-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
DOI:10.1172/JCI169225 PMID: 38051587 -
Xu B, Musai J, Tan YS, Hile GA, Swindell WR, Klein B, Qin JT, Sarkar MK, Gudjonsson JE, Kahlenberg JM. Frontiers in Lupus, 2024Journal ArticleA Critical Role for IFN-β Signaling for IFN-κ Induction in Keratinocytes
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Zhang H, Patrick MT, Tejasvi T, Sarkar MK, Wasikowski R, Stuart PE, Li Q, Xing X, Voorhees JJ, Ward NL, He K, Zhou X, Gudjonsson JE, Nair RP, Elder JT, Tsoi LC. Br J Dermatol, 2023 Dec 20; 190 (1): 70 - 79.Journal ArticleRetrospective pharmacogenetic study of psoriasis highlights the role of KLK7 in tumour necrosis factor signalling.
DOI:10.1093/bjd/ljad332 PMID: 37672660 -
Dand N, Stuart PE, Bowes J, Ellinghaus D, Nititham J, Saklatvala JR, Teder-Laving M, Thomas LF, Traks T, Uebe S, Assmann G, Baudry D, Behrens F, Billi AC, Brown MA, Burkhardt H, Capon F, Chung R, Curtis CJ, Duckworth M, Ellinghaus E, FitzGerald O, Gerdes S, Griffiths CEM, Gulliver S, Helliwell P, Ho P, Hoffmann P, Holmen OL, Huang Z-M, Hveem K, Jadon D, Köhm M, Kraus C, Lamacchia C, Lee SH, Ma F, Mahil SK, McHugh N, McManus R, Modalsli EH, Nissen MJ, Nöthen M, Oji V, Oksenberg JR, Patrick MT, Perez-White BE, Ramming A, Rech J, Rosen C, Sarkar MK, Schett G, Schmidt B, Tejasvi T, Traupe H, Voorhees JJ, Wacker EM, Warren RB, Wasikowski R, Weidinger S, Wen X, Zhang Z, BSTOP study group , Estonian Biobank research team , Barton A, Chandran V, Esko T, Foerster J, Franke A, Gladman DD, Gudjonsson JE, Gulliver W, Hüffmeier U, Kingo K, Kõks S, Liao W, Løset M, Mägi R, Nair RP, Rahman P, Reis A, Smith CH, Di Meglio P, Barker JN, Tsoi LC, Simpson MA, Elder JT. 2023 Oct 5;PreprintGWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.
DOI:10.1101/2023.10.04.23296543 PMID: 37873414 -
Schmauch E, Severin Y, Xing X, Mangold A, Conrad C, Johannsen P, Kahlenberg M, Mellett M, Navarini A, Nobbe S, Sarkar MK, Satyam A, Tsoi LC, French LE, Linna-Kuosmanen S, Kaikkonen MU, Snijder B, Kellis M, Gudjonsson JE, Tsokos GC, Contassot E, Kolios AGA. 2023 Oct 1;Journal ArticleTargeting IL-1 controls refractory Pityriasis rubra pilaris
DOI:10.21203/rs.3.rs-3433295/v1