Yuanfang Guan, PhD
Associate Professor of Computational Medicine and Bioinformatics
Associate Professor of Internal Medicine
[email protected]

Available to mentor
Yuanfang Guan, PhD
Associate Professor
  • Qualifications
  • Research Overview
  • Links
  • Recent Publications
    • Qualifications
    • Ph.D., Molecular Biology
      Princeton University, Princeton, NJ, 2010
    • BS, Biology
      The University of Hong Kong, Hong Kong, 2005
    Research Overview

    The Guan lab's research focus is machine learning in biology and medical fields.

    Links
    • Guan Lab
    Recent Publications See All Publications
    • Journal Article
      ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice.
      Schuster KH, Zalon AJ, DiFranco DM, Putka AF, Stec NR, Jarrah SI, Naeem A, Haque Z, Zhang H, Guan Y, McLoughlin HS. Mol Ther, 2024 Feb 29; DOI:10.1016/j.ymthe.2024.02.033
      PMID: 38429929
    • Journal Article
      Assessing the impact of body location on the accuracy of detecting daily activities with accelerometer data.
      Dang X, Li W, Zou J, Cong B, Guan Y. iScience, 2024 Feb 16; 27 (2): 108626 DOI:10.1016/j.isci.2023.108626
      PMID: 38318391
    • Journal Article
      Artificial intelligence approaches for molecular representation in drug response prediction.
      Lin C-X, Guan Y, Li H-D. Curr Opin Struct Biol, 2024 Feb; 84: 102747 DOI:10.1016/j.sbi.2023.102747
      PMID: 38091924
    • Journal Article
      Predicting Single Neuron Responses of the Primary Visual Cortex with Deep Learning Model.
      Deng K, Schwendeman PS, Guan Y. Adv Sci (Weinh), 2024 Apr; 11 (15): e2305626 DOI:10.1002/advs.202305626
      PMID: 38350735
    • Journal Article
      Harmonizing across datasets to improve the transferability of drug combination prediction.
      Zhang H, Wang Z, Nan Y, Zagidullin B, Yi D, Tang J, Guan Y. Commun Biol, 2023 Apr 11; 6 (1): 397 DOI:10.1038/s42003-023-04783-5
      PMID: 37041243
    • Journal Article
      Mapping combinatorial drug effects to DNA damage response kinase inhibitors.
      Zhang H, Kreis J, Schelhorn S-E, Dahmen H, Grombacher T, Zühlsdorf M, Zenke FT, Guan Y. Nat Commun, 2023 Dec 14; 14 (1): 8310 DOI:10.1038/s41467-023-44108-y
      PMID: 38097586
    • Journal Article
      Systematic dissection of genomic features determining the vast diversity of conotoxins.
      Zheng J-W, Lu Y, Yang Y-F, Huang D, Li D-W, Wang X, Gao Y, Yang W-D, Guan Y, Li H-Y. BMC Genomics, 2023 Oct 9; 24 (1): 598 DOI:10.1186/s12864-023-09689-4
      PMID: 37814244
    • Journal Article
      The ENCODE Imputation Challenge: a critical assessment of methods for cross-cell type imputation of epigenomic profiles.
      Schreiber J, Boix C, Wook Lee J, Li H, Guan Y, Chang C-C, Chang J-C, Hawkins-Hooker A, Schölkopf B, Schweikert G, Carulla MR, Canakoglu A, Guzzo F, Nanni L, Masseroli M, Carman MJ, Pinoli P, Hong C, Yip KY, Spence JP, Batra SS, Song YS, Mahony S, Zhang Z, Tan W, Shen Y, Sun Y, Shi M, Adrian J, Sandstrom R, Farrell N, Halow J, Lee K, Jiang L, Yang X, Epstein C, Strattan JS, Bernstein B, Snyder M, Kellis M, Stafford W, Kundaje A, ENCODE Imputation Challenge Participants . Genome Biol, 2023 Apr 18; 24 (1): 79 DOI:10.1186/s13059-023-02915-y
      PMID: 37072822