Weichen (Arthur) Zhou, PhD
Research Investigator
Computational Medicine and Bioinformatics
Department of Computational Medicine & Bioinformatics
Palmer Commons #2055, 100 Washtenaw Ave
Ann Arbor, MI 48109
[email protected]

Available to mentor
Weichen (Arthur) Zhou, PhD
Research Investigator
  • Qualifications
  • Links
  • Recent Publications
    • Qualifications
    • Ph.D., Genetics
      Fudan University, Shanghai, 2014
    • B.S.E., Bioinformatics
      Huazhong University of Science and Technology, Wuhan, 2009
    Links
    • https://scholar.google.com.hk/citations?user=3O6XCBkAAAAJ&hl=en
    • GitHub
    Recent Publications See All Publications
    • Journal Article
      Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases.
      Garrison MA, Jang Y, Bae T, Cherskov A, Emery SB, Fasching L, Jones A, Moldovan JB, Molitor C, Pochareddy S, Peters MA, Shin JH, Wang Y, Yang X, Akbarian S, Chess A, Gage FH, Gleeson JG, Kidd JM, McConnell M, Mills RE, Moran JV, Park PJ, Sestan N, Urban AE, Vaccarino FM, Walsh CA, Weinberger DR, Wheelan SJ, Abyzov A, BSMN Consortium . Sci Data, 2023 Nov 20; 10 (1): 813 DOI:10.1038/s41597-023-02645-7
      PMID: 37985666
    • Journal Article
      Assembly of 43 human Y chromosomes reveals extensive complexity and variation.
      Hallast P, Ebert P, Loftus M, Yilmaz F, Audano PA, Logsdon GA, Bonder MJ, Zhou W, Höps W, Kim K, Li C, Hoyt SJ, Dishuck PC, Porubsky D, Tsetsos F, Kwon JY, Zhu Q, Munson KM, Hasenfeld P, Harvey WT, Lewis AP, Kordosky J, Hoekzema K, Human Genome Structural Variation Consortium (HGSVC) , O'Neill RJ, Korbel JO, Tyler-Smith C, Eichler EE, Shi X, Beck CR, Marschall T, Konkel MK, Lee C. Nature, 2023 Sep; 621 (7978): 355 - 364. DOI:10.1038/s41586-023-06425-6
      PMID: 37612510
    • Journal Article
      Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions.
      Maury EA, Sherman MA, Genovese G, Gilgenast TG, Kamath T, Burris SJ, Rajarajan P, Flaherty E, Akbarian S, Chess A, McCarroll SA, Loh P-R, Phillips-Cremins JE, Brennand KJ, Macosko EZ, Walters JTR, O'Donovan M, Sullivan P, Psychiatric Genomic Consortium Schizophrenia and CNV workgroup , Brain Somatic Mosaicism Network , Sebat J, Lee EA, Walsh CA. Cell Genom, 2023 Aug 9; 3 (8): 100356 DOI:10.1016/j.xgen.2023.100356
      PMID: 37601975
    • Journal Article
      Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts.
      Zhou W, Karan KR, Gu W, Klein H-U, Sturm G, De Jager PL, Bennett DA, Hirano M, Picard M, Mills RE. bioRxiv, 2023 Apr 21; DOI:10.1101/2023.02.03.527065
      PMID: 36778249
    • Journal Article
      Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development.
      Chung C, Yang X, Bae T, Vong KI, Mittal S, Donkels C, Westley Phillips H, Li Z, Marsh APL, Breuss MW, Ball LL, Garcia CAB, George RD, Gu J, Xu M, Barrows C, James KN, Stanley V, Nidhiry AS, Khoury S, Howe G, Riley E, Xu X, Copeland B, Wang Y, Kim SH, Kang H-C, Schulze-Bonhage A, Haas CA, Urbach H, Prinz M, Limbrick DD, Gurnett CA, Smyth MD, Sattar S, Nespeca M, Gonda DD, Imai K, Takahashi Y, Chen H-H, Tsai J-W, Conti V, Guerrini R, Devinsky O, Silva WA, Machado HR, Mathern GW, Abyzov A, Baldassari S, Baulac S, Focal Cortical Dysplasia Neurogenetics Consortium , Brain Somatic Mosaicism Network , Gleeson JG. Nat Genet, 2023 Feb; 55 (2): 209 - 220. DOI:10.1038/s41588-022-01276-9
      PMID: 36635388
    • Journal Article
      A Molecular Mechanism of Stress-Induced Alzheimer’s Disease; Part 1
      Chapman MR, Zhou W, Yeh G. Journal of Macromolecular Science, Part B: Physics, 2023 Jan 1; 62 (10): 543 - 556. DOI:10.1080/00222348.2023.2228588
    • Journal Article
      Control-independent mosaic single nucleotide variant detection with DeepMosaic.
      Yang X, Xu X, Breuss MW, Antaki D, Ball LL, Chung C, Shen J, Li C, George RD, Wang Y, Bae T, Cheng Y, Abyzov A, Wei L, Alexandrov LB, Sebat JL, NIMH Brain Somatic Mosaicism Network , Gleeson JG. Nat Biotechnol, 2023 Jun; 41 (6): 870 - 877. DOI:10.1038/s41587-022-01559-w
      PMID: 36593400
    • Journal Article
      High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios.
      Byrska-Bishop M, Evani US, Zhao X, Basile AO, Abel HJ, Regier AA, Corvelo A, Clarke WE, Musunuri R, Nagulapalli K, Fairley S, Runnels A, Winterkorn L, Lowy E, Human Genome Structural Variation Consortium , Paul Flicek , Germer S, Brand H, Hall IM, Talkowski ME, Narzisi G, Zody MC. Cell, 2022 Sep 1; 185 (18): 3426 - 3440.e19. DOI:10.1016/j.cell.2022.08.004
      PMID: 36055201