An automated open-source program improves performance in creating high-fidelity stable folds for de novo protein design

DCMB researchers, including first author Robin Pearce, a Ph.D. candidate working under the mentorship of Gil S. Omenn, MD, Ph.D. developed FoldDesign, a new program that can create new and stable protein structures.

It is automated and open-source, and is better at creating these structures than other methods. This could lead to new medical and industrial uses.

Read the full research article "De novo protein fold design through sequence-independent fragment assembly simulations" in PNAS.