Areas of Interest
Our goal is to understand the communication mechanisms governing gene expression in mammalian cells with a single-cell and single-molecule resolutions. To do so, we leverage 3D genome mapping technologies to capture the dynamic chromatin interactions and study gene regulation in the context of developmental biology. Interpreting these high-throughput sequencing data probing the (3D) genome, epigenome, and transcriptome requires sophisticated algorithms and computational tools, which we develop by using ideas from signal processing, graph theory, information theory, and coding theory.
We welcome individuals from any background to join our research group and perform experimental techniques and/or develop computational algorithms.