August 1, 2024

CPOD Faculty Publication Spotlight - Feldman Lab

Eid S A, Elzinga S E, Guo K, Hinder L M, Hayes J M, Pacut C M, Koubek E J, Hur J, Feldman E L. Translational Research. 2024 August. 
Transcriptomic profiling of sciatic nerves and dorsal root ganglia reveals site-specific effects of prediabetic neuropathy.
"Drs. Stephanie Eid and Eva Feldman et al. used RNAseq to understand the mechanisms underlying the distal-to-proximal progression of peripheral neuropathy in diet-induced obese animals. They found that the immune response, insulin signaling, and lipid metabolism were dysregulated both at distal and proximal sites, while oxidative stress was present only distally. These findings that are now published in Translational Research".
Pictured: Dr. Stéphanie Eid, Ph.D. (Research Assistant Professor, Neurology, University of Michigan)