Associate Research Scientist
Emeritus
Dermatology
[email protected]
Available to mentor
Rajan P Nair
Associate Research Scientist Emeritus/a
Rajan Nair, PhD graduated from the University of Kerala, India, and received additional postdoctoral training at the Medical College of Georgia and the University of Michigan. His research interest has been the genetic analysis of psoriasis since he joined the Department of Dermatology in 1991. He helped develop a robust molecular genetics program in the Department, and his work has produced internationally acclaimed publications on the molecular genetics of psoriasis. Dr. Nair's research has focused on studies to understand the molecular basis of psoriasis pathogenesis.
Molecular genetic basis of psoriasis pathogenesis
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Zhang H, Patrick MT, Tejasvi T, Sarkar MK, Wasikowski R, Stuart PE, Li Q, Xing X, Voorhees JJ, Ward NL, He K, Zhou X, Gudjonsson JE, Nair RP, Elder JT, Tsoi LC. Br J Dermatol, 2023 Dec 20; 190 (1): 70 - 79.Journal ArticleRetrospective pharmacogenetic study of psoriasis highlights the role of KLK7 in tumour necrosis factor signalling.
DOI:10.1093/bjd/ljad332 PMID: 37672660 -
Ogawa K, Tsoi LC, Tanaka H, Kanai M, Stuart PE, Nair RP, Tanaka Y, Mochizuki H, Elder JT, Okada Y. J Invest Dermatol, 2023 Sep; 143 (9): 1813 - 1816.e2.Journal ArticleA Cross-Trait Genetic Correlation Study Identified Eight Diseases and Traits Associated with Psoriasis.
DOI:10.1016/j.jid.2023.01.037 PMID: 36906125 -
Patrick MT, Nair RP, He K, Stuart PE, Billi AC, Zhou X, Gudjonsson JE, Oksenberg JR, Elder JT, Tsoi LC. Ann Neurol, 2023 Aug; 94 (2): 384 - 397.Journal ArticleShared Genetic Risk Factors for Multiple Sclerosis/Psoriasis Suggest Involvement of Interleukin-17 and Janus Kinase-Signal Transducers and Activators of Transcription Signaling.
DOI:10.1002/ana.26672 PMID: 37127916 -
Tsoi LC, Zhang Z, Stuart P, Dand N, Patrick M, Simpson MA, Voorhees J, Barker J, Nair R, Elder JT. Journal of Investigative Dermatology, 2022 Aug; 142 (8): s80Journal Article471 Integrated psoriasis GWAS and eQTL analysis reveals risk-associated genetic control of TRAF3IP2-AS1 expression in activated CD8 T-cells
DOI:10.1016/j.jid.2022.05.480 -
Ellis CN, Neville SJ, Sayyouh M, Elder JT, Nair RP, Gudjonsson JE, Ma T, Kazerooni EA, Rubenfire M, Agarwal PP. J Am Acad Dermatol, 2022 Mar; 86 (3): 535 - 543.Journal ArticleEpicardial adipose tissue volume is greater in men with severe psoriasis, implying an increased cardiovascular disease risk: A cross-sectional study.
DOI:10.1016/j.jaad.2021.09.069 PMID: 34678237 -
Stuart PE, Tsoi LC, Nair RP, Ghosh M, Kabra M, Shaiq PA, Raja GK, Qamar R, Thelma BK, Patrick MT, Parihar A, Singh S, Khandpur S, Kumar U, Wittig M, Degenhardt F, Tejasvi T, Voorhees JJ, Weidinger S, Franke A, Abecasis GR, Sharma VK, Elder JT. HGG Adv, 2022 Jan 13; 3 (1):Journal ArticleTransethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine-mapping in the MHC and genomewide.
DOI:10.1016/j.xhgg.2021.100069 PMID: 34927100 -
Ahn R, Vukcevic D, Motyer A, Nititham J, Squire DM, Hollenbach JA, Norman PJ, Ellinghaus E, Nair RP, Tsoi LC, Oksenberg J, Foerster J, Lieb W, Weidinger S, Franke A, Elder JT, Jorgenson E, Leslie S, Liao W. Front Immunol, 2021 12: 684326Journal ArticleLarge-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis.
DOI:10.3389/fimmu.2021.684326 PMID: 34177931 -
Patrick MT, Stuart PE, Zhang H, Zhao Q, Yin X, He K, Zhou X-J, Mehta NN, Voorhees JJ, Boehnke M, Gudjonsson JE, Nair RP, Handelman SK, Elder JT, Liu DJ, Tsoi LC. J Invest Dermatol, 2021 Jun; 141 (6): 1493 - 1502.Journal ArticleCausal Relationship and Shared Genetic Loci between Psoriasis and Type 2 Diabetes through Trans-Disease Meta-Analysis.
DOI:10.1016/j.jid.2020.11.025 PMID: 33385400
Department News
Rajan P. Nair, PhD Retires from the University of Michigan's Department of Dermatology.
